Corticotropin-Releasing Hormone

A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.

Also Known As:

ACTH-Releasing Factor; CRF (ACTH); Corticoliberin; Corticotropin-Releasing Factor-41; ACTH Releasing Factor; ACTH Releasing Hormone; Corticotropin Releasing Factor; Corticotropin Releasing Factor 41; Corticotropin Releasing Hormone; Corticotropin Releasing Hormone 41; ACTH-Releasing Hormone; CRF-41; Corticotropin-Releasing Factor; Corticotropin-Releasing Hormone-41

Pharmalogical Action Categories:

Hormones

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - Hypothalamic Hormones: 68
        Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
- Peptides: 82426
  - Neuropeptides: 6772
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046
  - Peptide Hormones: 1347
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Corticotropin-Releasing Hormone: 2046

Pro(5)- corticotropin-releasing hormone

Bio-Agent Context: Research Results