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machilin D

from Saururus chinensis (Saururaceae); structure in first source

Also Known As:

8-O-4'-type neolignan

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Lignans: 1113
        machilin D: 3

Experts

1.	Choi, Hack Sun: 1 article (01/2020)
2.	Kim, Ji-Hyang: 1 article (01/2020)
3.	Kim, Su-Lim: 1 article (01/2020)
4.	Lee, Dong-Sun: 1 article (01/2020)
5.	Liu, Ren: 1 article (01/2020)
6.	Yun, Bong-Sik: 1 article (01/2020)
7.	Zhen, Xing: 1 article (01/2020)
8.	Chang, Hyun-Wook: 1 article (03/2008)
9.	Jahng, Yurngdong: 1 article (03/2008)
10.	Jung, Jun-Sub: 1 article (03/2008)

Related Diseases

1.	Sepsis (Septicemia) 03/01/2008 - "In the course of isolating preventive agents from sepsis based on the in vivo assay model from the EtOAc extract of the roots of Saururus chinensis, twelve lignans, sarisan (1), erythro-austrobailignan-6 (2), meso-dihydroguaiaretic acid (3), saucerneol B (4), manassantin B (5), manassantin A (6), rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan (7), (+)-saururinone (8), sauchinone (9), sauchinone B (10), nectandrin B (11) and machilin D (12), were isolated. "
2.	Neoplasms (Cancer) 01/01/2020 - "Machilin D inhibited the growth and mammosphere formation of breast cancer cells and inhibited tumor growth in a xenograft mouse model. "
3.	Breast Neoplasms (Breast Cancer) 01/01/2020 - "Machilin D inhibited the growth and mammosphere formation of breast cancer cells and inhibited tumor growth in a xenograft mouse model. " 01/01/2020 - "Machilin D, a Lignin Derived from Saururus chinensis, Suppresses Breast Cancer Stem Cells and Inhibits NF-κB Signaling."
4.	Squamous Cell Carcinoma of Head and Neck 02/26/2023 - "Machilin D Promotes Apoptosis and Autophagy, and Inhibits Necroptosis in Human Oral Squamous Cell Carcinoma Cells."

Related Drugs and Biologics

1.	Lignans
2.	Lignin
3.	nectandrin-B
4.	erythro-austrobailignan-6
5.	manassantin B
6.	saucerneol B
7.	sauchinone
8.	sarisan
9.	manassantin A
10.	dihydroguaiaretic acid