ligstroside

structure in first source

Also Known As:

ligustroside; 2H-Pyran-4-acetic acid, 3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(4-hydroxyphenyl)ethyl ester, (2S,3E,4S)-

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Glucosides: 639
    - ligstroside: 7
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - ligstroside: 7

Experts

1.	Kim, Hojun: 1 article (02/2022)
2.	Kong, Chang-Suk: 1 article (02/2022)
3.	Seo, Youngwan: 1 article (02/2022)
4.	Alarcón-de-la-Lastra, Catalina: 1 article (01/2020)
5.	Dilberger, Benjamin: 1 article (01/2020)
6.	Eckert, Gunter P: 1 article (01/2020)
7.	Fernández-Bolaños, Jose G: 1 article (01/2020)
8.	Fuchs, Christopher: 1 article (01/2020)
9.	González-Benjumea, Alejandro: 1 article (01/2020)
10.	Grewal, Rekha: 1 article (01/2020)

Related Diseases

1.	Osteoarthritis 01/01/2020 - "Our study demonstrated that a new synthetic acetylated ligstroside aglycone derivative offers enhanced anti-inflammatory profile than the natural nutraceutical compound in osteoarthritis. " 01/01/2020 - "Osteoarthritis treatment with a novel nutraceutical acetylated ligstroside aglycone, a chemically modified extra-virgin olive oil polyphenol." 01/01/2020 - "Acetylated ligstroside aglycone significantly reduced the expression of pro-inflammatory genes including NOS2 and MMP13 at both RNA and protein levels; decreased nitric oxide release; and, importantly, reduced proteoglycan loss in human osteoarthritis cartilage explants. "
2.	Neoplasms (Cancer) 05/29/2023 - "This study evaluated the synergistic anti-proliferative/cytotoxic effects of five olive secoiridoid derivatives (oleocanthal, oleacein, oleuropein aglycone, ligstroside aglycone and oleomissional) in all possible double combinations and of total phenolic extracts (TPEs) on eleven human cancer cell lines representing eight cell-culture-based cancer models. "
3.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2020 - "Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing." 01/01/2020 - "Since mitochondrial dysfunction is involved in both, brain ageing and early AD, effects of 10 different purified phenolic secoiridoids (hydroxytyrosol, tyrosol, oleacein, oleuroside, oleuroside aglycon, oleuropein, oleocanthal, ligstroside, ligstroside aglycone and ligustaloside B) and two metabolites (the plant metabolite elenolic acid and the mammalian metabolite homovanillic acid) were tested in very low doses on mitochondrial function in SH-SY5Y-APP695 cells - a cellular model of early AD. "
4.	Paramyxoviridae Infections (Parainfluenza) 11/01/2001 - "Six secoiridoid glucosides, lucidumoside C (1), oleoside dimethylester (2), neonuezhenide (3), oleuropein (4), ligustroside (5) and lucidumoside A (6), isolated from the fruits of Ligustrum lucidum (Oleaceae), were examined in vitro for their activities against four strains of pathogenic viruses, namely herpes simplex type I virus (HSV-1), influenza type A virus (Flu A), respiratory syncytial virus (RSV) and parainfluenza type 3 virus (Para 3). "
5.	Liver Neoplasms (Liver Cancer) 10/24/2019 - "The present work aimed to assess the effects of a polyphenolic extract containing both oleocanthal and ligstroside aglycone on proliferation and/or death in three liver cancer cell lines (HepG2, Huh7 and Hep3B). " 10/24/2019 - "Anti-Proliferative Effects of an Extra-Virgin Olive Oil Extract Enriched in Ligstroside Aglycone and Oleocanthal on Human Liver Cancer Cell Lines."

Related Drugs and Biologics

1.	oleocanthal
2.	oleacein
3.	oleuropein aglycone
4.	Olive Oil
5.	oleuropein
6.	Polyphenols
7.	Inflammasomes
8.	Iridoid Glucosides
9.	Iridoids
10.	RNA (Ribonucleic Acid)