HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

deoxymikanolide

sesquiterpene dilactone from Mikania cordata; structure in first source

Also Known As:

(1,10-epoxy-4,11(13)-germacradiene12,8-15,6-diolide); deoxy-mikanolide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - Monocyclic Sesquiterpenes: 14
        Germacrane Sesquiterpenes: 1
        deoxymikanolide: 3
- Lactones: 1549
  - deoxymikanolide: 3

Experts

1.	Laurella, Laura C: 2 articles (03/2019 - 09/2017)
2.	Martino, Virginia S: 2 articles (03/2019 - 09/2017)
3.	Sülsen, Valeria P: 2 articles (03/2019 - 09/2017)
4.	Lombardo, Elisa: 1 article (03/2019)
5.	Lozano, Esteban: 1 article (03/2019)
6.	Puente, Vanesa: 1 article (03/2019)
7.	Sosa, Miguel A: 1 article (03/2019)
8.	Spina, Renata M: 1 article (03/2019)
9.	Aliança, Amanda Silva Dos Santos: 1 article (01/2019)
10.	Brelaz-de-Castro, Maria Carolina Accioly: 1 article (01/2019)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 03/15/2019 - "Deoxymikanolide did not affect the intracellular redox state and so the mitochondrial dysfunction produced by this compound could not be attributed to ROS generation. " 03/15/2019 - "Based on our results, deoxymikanolide would exert its anti-T cruzi activity as a strong thiol blocking agent and by producing mitochondrial dysfunction."
2.	Parasitemia 09/01/2017 - "In an in vivo model of Trypanosoma cruzi infection, deoxymikanolide was able to decrease the parasitemia and the weight loss associated to the acute phase of the parasite infection. "
3.	Weight Loss (Weight Reduction) 09/01/2017 - "In an in vivo model of Trypanosoma cruzi infection, deoxymikanolide was able to decrease the parasitemia and the weight loss associated to the acute phase of the parasite infection. "
4.	Chagas Disease (American Trypanosomiasis) 09/01/2017 - "In an in vivo model of Trypanosoma cruzi infection, deoxymikanolide was able to decrease the parasitemia and the weight loss associated to the acute phase of the parasite infection. "
5.	Parasitic Diseases (Parasitic Disease) 09/01/2017 - "In an in vivo model of Trypanosoma cruzi infection, deoxymikanolide was able to decrease the parasitemia and the weight loss associated to the acute phase of the parasite infection. "

Related Drugs and Biologics

1.	Thomsen-Friedenreich antibodies
2.	Sulfhydryl Compounds (Thiols)
3.	Ursolic Acid
4.	Rosmarinic Acid
5.	lipoarabinomannan (LAM)
6.	ferulic acid (sodium ferulate)