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falcipain 3

a trophozoite-specific enzyme localized in the food vacuole; GenBank AF282974

Also Known As:

falcipain-3; hemoglobinase falcipain-3

Networked: 14 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        falcipain 3: 14
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        falcipain 3: 14

Experts

1.	Rosenthal, Philip J: 8 articles (01/2020 - 01/2003)
2.	Sijwali, Puran S: 3 articles (08/2007 - 11/2006)
3.	Pandey, Kailash C: 2 articles (01/2012 - 02/2009)
4.	Singh, Ajay: 2 articles (04/2007 - 12/2003)
5.	Lee, Belinda J: 2 articles (12/2003 - 01/2003)
6.	Chauhan, Monika: 1 article (12/2021)
7.	Dhingra, Neelima: 1 article (12/2021)
8.	Gorki, Varun: 1 article (12/2021)
9.	Kaur, Sukhbir: 1 article (12/2021)
10.	Walter, Neha Sylvia: 1 article (12/2021)

Related Diseases

1.	Malaria 08/01/2015 - "Falcipain-3 (FP3) is an essential and drug target cysteine protease of the most lethal human malaria parasite Plasmodium falciparum. " 09/01/2013 - "Falcipain-3, the major cysteine hemoglobinase from the human malaria parasite Plasmodium falciparum, is critical for parasite development and is considered as a promising chemotherapeutic target. " 01/01/2012 - "Overall, the complexes of falcipain-2 and falcipain-3 with small and macromolecular inhibitors provide structural insight to facilitate the design or modification of effective drug treatment against malaria. " 02/12/2009 - "Falcipain-2 and falcipain-3 are critical hemoglobinases of Plasmodium falciparum, the most virulent human malaria parasite. " 11/01/2006 - "Our data suggest key roles for falcipain-2 and falcipain-3 in the development of erythrocytic malaria parasites and a complex interplay between P. "
2.	Infections 01/01/2020 - "Falcipain-2 and falcipain-3 play vital roles during the erythrocytic stage of infection with P. "

Related Drugs and Biologics

1.	Artesunate
2.	sinigrin
3.	falcipain 2
4.	Cysteine Proteases (Cysteine Protease)
5.	Hemoglobins (Hemoglobin)
6.	Enzymes
7.	Amino Acids
8.	Proteins (Proteins, Gene)
9.	Papain
10.	Cysteine (L-Cysteine)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)