a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells
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Bio-Agent Context: Research Results
|1. ||Neoplasms (Cancer)
- "Five labdane-type diterpenes, vitexilactone (1), (rel 5S,6R,8R,9R,10S)-6-acetoxy-9-hydroxy-13(14)-labden-16,15-olide (2), rotundifuran (3), vitetrifolin D (4), and vitetrifolin E (5), have been isolated from Vitex trifolia L., a Chinese folk medicine used to treat cancers, as new cell cycle inhibitors and apoptosis inducers through a bioassay-guided separation procedure and were identified by spectroscopic methods.
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