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26-hydroxy-22-methylcycloirid-16-enal

a phorbol ester receptor ligand; structure in first source

Also Known As:

NSC 631939; NSC-631939; NSC631939; iripallidal

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Dixit, Deobrat: 1 article (06/2010)
2.	Ghosh, Sadashib: 1 article (06/2010)
3.	Koul, Nitin: 1 article (06/2010)
4.	Sen, Ellora: 1 article (06/2010)
5.	Sharma, Vivek: 1 article (06/2010)

Related Diseases

1.	Glioblastoma (Glioblastoma Multiforme) 06/24/2010 - "The highly resistant nature of glioblastoma multiforme (GBM) to chemotherapy prompted us to evaluate the efficacy of bicyclic triterpenoid Iripallidal against GBM in vitro. "
2.	Neoplasms (Cancer) 06/24/2010 - "In addition, Iripallidal displayed anti-proliferative activity against non-glioma cancer cell lines of diverse origin. "
3.	Glioma (Gliomas) 06/24/2010 - "In addition, Iripallidal displayed anti-proliferative activity against non-glioma cancer cell lines of diverse origin. " 06/24/2010 - "Iripallidal (i) induced apoptosis, (ii) inhibited Akt/mTOR and STAT3 signaling, (iii) altered molecules associated with cell cycle and DNA damage, (iv) inhibited telomerase activity and colony forming efficiency of glioma cells. " 06/24/2010 - "The effect of Iripallidal on proliferation and apoptosis in glioma cell lines was evaluated by MTS, colony formation and caspase-3 activity. " 06/24/2010 - "Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells."

Related Drugs and Biologics

1.	Triterpenes
2.	Caspase 3 (Caspase-3)
3.	Telomerase (Telomerase Reverse Transcriptase)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)