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(5- fluoro- 2- methyl- 1- (4- pyridyl)methylene- 3- (N- benzyl)- indene)- acetamide hydrochloride

a selective apoptotic antineoplastic agent (SAAND) that inhibits cyclic-GMP phosphodiesterase and causes microtubule depolymerization
Also Known As:
CP 461; CP-461; CP461 cpd; OSI 461; OSI-461; OSI461
Networked: 8 relevant articles (1 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Deguchi, Atsuko: 3 articles (01/2006 - 10/2004)
2. Weinstein, I Bernard: 3 articles (01/2006 - 10/2004)
3. Oehlen, Bert: 2 articles (01/2006 - 09/2005)
4. Xiao, Danhua: 2 articles (01/2006 - 10/2004)
5. Schroeder, Thomas: 1 article (02/2012)
6. Wilk, Christian Matthias: 1 article (02/2012)
7. Haas, Rainer: 1 article (02/2012)
8. Brünnert, Daniela: 1 article (02/2012)
9. Czibere, Akos: 1 article (02/2012)
10. Cadeddu, Ron-Patrick: 1 article (02/2012)

Related Diseases

1. Hepatocellular Carcinoma (Hepatoma)
2. Neoplasms (Cancer)
3. Prostatic Neoplasms (Prostate Cancer)
4. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
5. Crohn Disease (Crohn's Disease)

Related Drugs and Biologics

1. 3,7,11,15- tetramethyl- 2,4,6,10,14- hexadecapentaenoic acid
2. Sulindac (Copal)
3. Prednisone (Sone)
4. Mitoxantrone (Novantrone)
5. sulindac sulfone (exisulind)
6. Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)
7. Cyclic GMP
8. Phosphoric Diester Hydrolases (Phosphodiesterases)
9. Cyclooxygenase 1
10. Hormones

Related Therapies and Procedures

1. Chemoprevention
2. Drug Therapy (Chemotherapy)
3. Withholding Treatment