coronin

01/01/2020 - "Interestingly, these vesicles contain melanosome markers suggesting a melanoma-specific mechanism of EV release, regulated by Coronin 1C, that contributes to the high rates of metastasis in melanoma."
01/01/2020 - "Loss of Coronin 1C in this model increases both primary tumor growth rates and distant metastases. "
01/01/2020 - "Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion."
09/14/2012 - "Coronin 3 is highly expressed in gastric cancer metastases and can promote the metastatic behaviors of gastric cancer cells, including their migration and invasion."
09/14/2012 - "In addition, knockdown of coronin 3 significantly reduced liver metastasis in mice after tail vein injection of gastric cancer cells. "

09/01/2017 - "The present study demonstrated that coronin 3 is significantly upregulated in clinical primary hepatocellular carcinoma (HCC) samples by reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) and immunohistochemical staining. "
01/01/2021 - "Coronin 6 promotes hepatocellular carcinoma progression by enhancing canonical Wnt/beta-catenin signaling pathway."
09/14/2012 - "Coronin 3 is also associated with the aggression and metastasis of hepatocellular carcinoma. "

12/01/2018 - "Here, we investigated the contribution of coronin 1C to the invasive potential of breast cancer cells. "
12/01/2018 - "These results identify coronin 1C as a novel player of the multi-faceted mechanism responsible for invadopodia formation, MT1-MMP surface exposure and invasiveness in breast cancer cells."
12/01/2018 - "Using intravital imaging of orthotopic human breast tumor xenografts, we find that coronin 1C accumulates in structures forming in association with collagen fibrils in the tumor microenvironment. "
08/28/2018 - "RESULTS The expressions of Coronin 1c and F-actin in breast cancer tissues were positively correlated (r=0.926, P<0.05) and were significantly higher than those in normal tissues (P<0.05). "
08/28/2018 - "We analyzed the relationship between Coronin 1c and F-actin and clinical data of breast cancer. "

01/01/2008 - "In addition to reviewing the molecular signals and events that lead to Coronin 1C transcription, we summarize the results of several studies describing the possible functional roles of Coronin 1C in development as well as disease progression. "

01/01/2020 - "Coronin 3 was found to be highly upregulated in glioma cell lines. "
01/01/2020 - "However, little is known about the role of Coronin 3 in glioma tumorigenesis. "
01/01/2020 - "Our study reveals a new molecular mechanism of Coronin 3 in promoting glioma growth and development through regulating the Wnt/β-catenin signaling pathway."
01/01/2020 - "Moreover, we demonstrated that Coronin 3 regulates the expression of β-catenin in glioma. "
01/01/2020 - "Coronin 3 Promotes the Development of Oncogenic Properties in Glioma Through the Wnt/β-Catenin Signaling Pathway."