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coronin

isolated from the roots of Annona muricata; structure in first source; do not confuse with coronin protein
Networked: 30 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Pieters, Jean: 10 articles (10/2015 - 07/2007)
2. Jayachandran, Rajesh: 4 articles (10/2015 - 07/2007)
3. Siegmund, Kerstin: 4 articles (12/2013 - 03/2011)
4. Clemen, Christoph S: 3 articles (01/2015 - 01/2008)
5. Bear, James E: 3 articles (06/2014 - 01/2008)
6. Ziemann, Anja: 2 articles (01/2015 - 05/2013)
7. BoseDasgupta, Somdeb: 2 articles (11/2014 - 04/2013)
8. Föger, Niko: 2 articles (06/2014 - 11/2008)
9. Miyake, Masaki: 2 articles (12/2008 - 05/2008)
10. Roadcap, David W: 2 articles (11/2008 - 01/2008)

Related Diseases

1. Disease Progression
2. Infection
3. Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
4. Neoplasms (Cancer)
01/01/2008 - "This review primarily focuses on Coronin 1C (HGNC symbol: CORO1C, also known as Coronin 3) which is a transcriptionally dynamic gene that is up-regulated in multiple types of clinically aggressive cancer. "
05/01/2013 - "Movement of tumor cells involves dynamic remodeling of the actin cytoskeleton, which is regulated by actin binding proteins, such as CRN2 (synonyms: coronin 1C, coronin 3). "
01/01/2012 - "Coronins are a family of highly evolutionary conserved proteins reportedly involved in the regulation of actin cytoskeletal dynamics, although only coronin 3 has been shown to be related to cancer cell migration. "
01/01/2012 - "The Human Tumor Metastasis PCR Array was used to screen the metastasis-associated genes identified by the down-regulation of coronin 3, and the results suggested that, following the knockdown of coronin 3, the tumor cell migration and invasion were inhibited by the reduced expression of MMP-9 and cathepsin K. "
12/03/2010 - "Up-regulated proteins in metastatic carcinomas included proliferating cell nuclear antigen, ferritin light chain, bomapin, tropomyosin 3, thioredoxin-containing domain C5, adenosin, ornithine aminotransferase, coronin 1A, RAN-binding protein 1,3-phosphoglycerate dehydrogenase, and eukaryotic translation elongation factor 1. Down-regulated proteins in metastatic carcinomas included calretinin, myosin, light chain 2, peroxiredoxin 6, maspin, ibrinogen beta chain, vinculin, isocitrate dehydrogenase 1, tropomyosin 1, annexin A5, and Rho GTPase activating protein 1. Interestingly, 19 of these 21 proteins have been described with a malignancy-associated expression in human breast cancer and other human cancer types before. "
5. Lymphopenia (Lymphocytopenia)

Related Drugs and Biologics

1. Carrier Proteins (Binding Protein)
2. Proteins (Proteins, Gene)
3. Actins (F Actin)
4. calretinin
5. Cathepsin K
6. Peroxiredoxin VI
7. Caveolin 1
8. Small Interfering RNA (siRNA)
9. Peptide Elongation Factor 1 (1, EF)
10. GTP Phosphohydrolases (GTPases)