|1.||Pieters, Jean: 10 articles (10/2015 - 07/2007)|
|2.||Jayachandran, Rajesh: 4 articles (10/2015 - 07/2007)|
|3.||Siegmund, Kerstin: 4 articles (12/2013 - 03/2011)|
|4.||Clemen, Christoph S: 3 articles (01/2015 - 01/2008)|
|5.||Bear, James E: 3 articles (06/2014 - 01/2008)|
|6.||Ziemann, Anja: 2 articles (01/2015 - 05/2013)|
|7.||BoseDasgupta, Somdeb: 2 articles (11/2014 - 04/2013)|
|8.||Föger, Niko: 2 articles (06/2014 - 11/2008)|
|9.||Miyake, Masaki: 2 articles (12/2008 - 05/2008)|
|10.||Roadcap, David W: 2 articles (11/2008 - 01/2008)|
11/03/2014 - "These results suggest that modulation of coronin 1 oligomerization is an effective way to determine the outcome of a mycobacterial infection in macrophages. "
05/01/2008 - "The exclusion of p57/coronin-1 from phagosomes containing live another Legionella species Legionella gratiana at an early stage of infection was also observed. "
07/13/2007 - "Upon infection, the leukocyte-specific protein coronin 1 is actively recruited to mycobacterial phagosomes, where it blocks lysosomal delivery by an unknown mechanism. "
12/01/2013 - "In this work, we have analyzed antiviral T cell-mediated immunity in the presence and absence of coronin 1 in vivo after infection with lymphocytic choriomenigitis virus (LCMV) and vesicular stomatitis virus (VSV) in mice. "
01/01/2014 - "Porcine coronin 1A contributes to nuclear factor-kappa B (NF-κB) inactivation during Haemophilus parasuis infection."
|3.||Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
10/01/2015 - "Coronin 1 is the most recent candidate in the list of genes causing severe combined immunodeficiency (SCID) in humans. "
12/01/2014 - "Whereas complete absence of coronin 1A is associated with severe combined immunodeficiency in humans, hypomorphic mutations lead to a profound defect in naïve T cells, expansion of oligoclonal memory T cells, and exquisite susceptibility to EBV-associated B cell lymphoproliferation. "
10/01/2013 - "We further used this method to bypass the embryonic requirement of cor-1, which encodes the homolog of human severe combined immunodeficiency (SCID) protein coronin, and we determined its essential role in cell migration in larval Q-cell lineages. "
11/01/2008 - "Our findings establish a function for coronin 1A in T cell egress, identify a surface of coronin involved in Arp2/3 regulation and demonstrate that actin regulation is a biological process defective in human and mouse severe combined immunodeficiency."
11/01/2008 - "The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency."
01/01/2008 - "This review primarily focuses on Coronin 1C (HGNC symbol: CORO1C, also known as Coronin 3) which is a transcriptionally dynamic gene that is up-regulated in multiple types of clinically aggressive cancer. "
05/01/2013 - "Movement of tumor cells involves dynamic remodeling of the actin cytoskeleton, which is regulated by actin binding proteins, such as CRN2 (synonyms: coronin 1C, coronin 3). "
01/01/2012 - "Coronins are a family of highly evolutionary conserved proteins reportedly involved in the regulation of actin cytoskeletal dynamics, although only coronin 3 has been shown to be related to cancer cell migration. "
01/01/2012 - "The Human Tumor Metastasis PCR Array was used to screen the metastasis-associated genes identified by the down-regulation of coronin 3, and the results suggested that, following the knockdown of coronin 3, the tumor cell migration and invasion were inhibited by the reduced expression of MMP-9 and cathepsin K. "
12/03/2010 - "Up-regulated proteins in metastatic carcinomas included proliferating cell nuclear antigen, ferritin light chain, bomapin, tropomyosin 3, thioredoxin-containing domain C5, adenosin, ornithine aminotransferase, coronin 1A, RAN-binding protein 1,3-phosphoglycerate dehydrogenase, and eukaryotic translation elongation factor 1. Down-regulated proteins in metastatic carcinomas included calretinin, myosin, light chain 2, peroxiredoxin 6, maspin, ibrinogen beta chain, vinculin, isocitrate dehydrogenase 1, tropomyosin 1, annexin A5, and Rho GTPase activating protein 1. Interestingly, 19 of these 21 proteins have been described with a malignancy-associated expression in human breast cancer and other human cancer types before. "
10/01/2015 - "A distinctive feature of the SCID induced by coronin 1 deficiency is selective naïve T cell lymphopenia in the presence of a normal thymus as well as normal B cell and natural killer cell numbers (T(-)B(+)NK(+)). "
12/01/2013 - "Both in mouse and in human, coronin 1 deficiency is associated with severe T cell lymphopenia. "
|1.||Carrier Proteins (Binding Protein)
|2.||Proteins (Proteins, Gene)
|3.||Actins (F Actin)
|8.||Small Interfering RNA (siRNA)
|9.||Peptide Elongation Factor 1 (1, EF)
|10.||GTP Phosphohydrolases (GTPases)