aspercetin

a platelet aggregating component from the venom of the snake Bothrops asper which induces thrombocytopenia and potentiates metalloproteinase-induced hemorrhage; N-terminal amino acid sequence in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Rucavado, Alexandra: 2 articles (03/2022 - 07/2005)
2.	Alfaro-Alarcón, Alejandro: 1 article (03/2022)
3.	Arias-Gómez, Berny: 1 article (03/2022)
4.	Barquero-Calvo, Elías: 1 article (03/2022)
5.	Chacón-Díaz, Carlos: 1 article (03/2022)
6.	Fonseca-Muñoz, Roger: 1 article (03/2022)
7.	Moreno, Edgardo: 1 article (03/2022)
8.	Arni, Raghuvir: 1 article (07/2005)
9.	Escalante, Teresa: 1 article (07/2005)
10.	Gutiérrez, José María: 1 article (07/2005)

Related Diseases

1.	Hemorrhage 04/01/2001 - "Moreover, aspercetin is not lethal, nor does it induce myonecrosis, hemorrhage and edema. " 07/01/2005 - "Neither aspercetin nor the defibrin(ogen)ating and hypoaggregating components induced hemorrhage upon intravenous injection. " 03/01/2022 - "Aspercetin does not induce systemic hemorrhage or inflammation, and when injected into mice, it generates a rapid dose-dependent drop in platelet counts without affecting central organs, disrupting hematological parameters, or the proinflammatory cytokine profile. " 04/01/2001 - "Characterization of aspercetin, a platelet aggregating component from the venom of the snake Bothrops asper which induces thrombocytopenia and potentiates metalloproteinase-induced hemorrhage."
2.	Thrombocytopenia (Thrombopenia) 04/01/2001 - "Characterization of aspercetin, a platelet aggregating component from the venom of the snake Bothrops asper which induces thrombocytopenia and potentiates metalloproteinase-induced hemorrhage." 11/01/2022 - "A profound thrombocytopenia was induced in mice by the administration of aspercetin, a C-type lectin-like protein that induces platelet agglutination and drop in platelet counts, while a control group was treated with saline solution instead. "
3.	Inflammation (Inflammations) 03/01/2022 - "Aspercetin does not induce systemic hemorrhage or inflammation, and when injected into mice, it generates a rapid dose-dependent drop in platelet counts without affecting central organs, disrupting hematological parameters, or the proinflammatory cytokine profile. "
4.	Edema (Dropsy) 04/01/2001 - "Moreover, aspercetin is not lethal, nor does it induce myonecrosis, hemorrhage and edema. "
5.	Brucellosis (Malta Fever) 03/01/2022 - "Following these reports, we explored the course of brucellosis in thrombocytopenic mice, using the non-toxic low-molecular-weight aspercetin protein that depletes platelets in vivo. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Metalloproteases (Metalloproteinases)
3.	C-Type Lectins (C-Type Lectin)
4.	Cytokines
5.	Venoms
6.	Saline Solution
7.	estropipate (Ogen)

Related Therapies and Procedures

1.	Intravenous Injections