HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
GGTI 286
the methyl ester of GGTI-287; inhibits geranylgeranyltransferase
Also Known As:
GGTI-286; GGTI286
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Branched-Chain Amino Acids: 2289
Leucine: 6718
GGTI 286: 1
Essential Amino Acids: 1152
Leucine: 6718
GGTI 286: 1
Related Diseases
1.
Glioma (Gliomas)
07/01/1998 - "
Our studies demonstrated that FTI-277, GGTI-286, and GGTI-298 each yielded significant antiproliferative effects in human malignant glioma cells in vitro at low micromolar concentrations, which have been achievable in vivo without major systemic toxicity.
"
07/01/1998 - "
FTI-277, GGTI-286, and GGTI-298 each produced a striking concentration-dependent antiproliferative effect on the glioma cell lines, with the median effective dose ranging from 2.5 to 15.5 micromol/L.
"
Related Drugs and Biologics
1.
GGTI 298
2.
FTI 277