|1.||Gmeiner, William H: 4 articles (02/2013 - 08/2002)|
|2.||Pardee, Timothy S: 1 article (02/2013)|
|3.||Jennings-Gee, Jamie: 1 article (02/2013)|
|4.||Pommier, Yves: 1 article (12/2010)|
|5.||Reinhold, William C: 1 article (12/2010)|
|6.||Wei, Cui: 1 article (01/2004)|
|7.||Trump, Eric: 1 article (01/2004)|
|8.||Liu, Jinqian: 1 article (08/2002)|
|9.||Liu, Changnian: 1 article (08/2002)|
|10.||Willingham, Mark: 1 article (08/2002)|
|1.||Colorectal Neoplasms (Colorectal Cancer)
06/01/1999 - "The cytotoxicity of the 10mer ODN FdUMP towards human colorectal tumor cells was evaluated using a clonogenic assay. "
08/24/2001 - "The folic acid conjugate FA-FdUMP showed improved cytotoxicity toward human colorectal tumor cells (H630), and 5-FU-resistant colorectal tumor cells (H630-10). "
08/24/2001 - "Targeted drug delivery to chemoresistant cells: folic acid derivatization of FdUMP enhances cytotoxicity toward 5-FU-resistant human colorectal tumor cells."
10/01/1999 - "The dose-response behaviors of 5-FU and FdUMP toward H630 and H630-10 (human colorectal tumor) cells were first investigated separately. "
10/01/1999 - "Positive interaction between 5-FU and FdUMP in the inhibition of human colorectal tumor cell proliferation."
|2.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
02/01/2013 - "The present studies were undertaken to clarify the relationship between the induction of a thymineless state and the formation of Top1 cleavage complexes (Top1CC) for inducing cell death and to clarify the role of DNA replication for induction of lethal DNA double-strand breaks (DSBs) in FdUMP-treated acute myeloid leukemia (AML) cells. "
12/01/2010 - "FdUMP had the largest dynamic range of any of these drugs across the NCI-60 indicative of cancer cell-specific activity. "
08/01/2002 - "Simultaneous treatment of tumor-bearing mice with both drugs (FdUMP plus 5-FU) further delayed tumor growth (T/C value = 36%; p=0.003 relative to 5-FU). "
08/01/2002 - "Treatment with FdUMP as a single agent (40 mg/kg/daily x 5, i.v.) delayed tumor growth and resulted in a smaller mean tumor size (T/C value = 51%, p<0.001 compared with the control group). "
|4.||Colonic Neoplasms (Colon Cancer)
|1.||Folic Acid (Vitamin M)
|2.||DNA (Deoxyribonucleic Acid)
|5.||Uridine Diphosphate Sugars
|8.||RNA (Ribonucleic Acid)
|9.||nucleoside-diphosphatase (nucleoside diphosphatase)
|1.||Heterologous Transplantation (Xenotransplantation)