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CT 50547

structure in first source

Also Known As:

CT50547

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - CT 50547: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - CT 50547: 1

Experts

1.	André, Patrick: 1 article (11/2003)
2.	Conley, Pamela B: 1 article (11/2003)
3.	Delaney, Suzanne M: 1 article (11/2003)
4.	LaRocca, Thomas: 1 article (11/2003)
5.	Lin, Pei Hua: 1 article (11/2003)
6.	Phillips, David R: 1 article (11/2003)
7.	Sinha, Uma: 1 article (11/2003)
8.	Vincent, Diana: 1 article (11/2003)

Related Diseases

1.

Thrombosis (Thrombus)

11/25/2003 - "In contrast, CT50547 inhibited thrombosis in aspirin-treated individuals independently of the anticoagulant. "
11/25/2003 - "CT50547, a direct-acting P2Y12 antagonist, inhibited thrombosis in PPACK- but not heparin-anticoagulated human blood. "
11/25/2003 - "Thrombin and TXA2 also synergized with P2Y12 in the absence of anticoagulation, because combined treatment of aspirin or C921-78 (a factor Xa inhibitor) with CT50547 or 2-MeSAMP (a P2Y12 antagonist) inhibited the thrombotic process, whereas all treatments failed to inhibit thrombosis when used individually. "

Related Drugs and Biologics

1.	Thrombin
2.	Heparin (Liquaemin)
3.	Aspirin (Acetylsalicylic Acid)
4.	Anticoagulants
5.	BnSO(2)-D-Arg-Gly-Arg-ketothiazole
6.	phenylalanyl- prolyl- arginine- chloromethyl ketone (PPACK)
7.	A-factor (Streptomyces)