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SU 9516

induces apoptosis in colon carcinoma cells; structure in first source

Also Known As:

3-(1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene)-5-methoxy-1,3-dihydro-indol-2-one; SU9516

Networked: 8 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - SU 9516: 8
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - SU 9516: 8

Experts

1.	Burkin, Dean J: 2 articles (01/2017 - 01/2017)
2.	Fontelonga, Tatiana M: 2 articles (01/2017 - 01/2017)
3.	Nunes, Andreia M: 2 articles (01/2017 - 01/2017)
4.	Sarathy, Apurva: 2 articles (01/2017 - 01/2017)
5.	Hatok, Jozef: 1 article (12/2017)
6.	Klačanová, Katarína: 1 article (12/2017)
7.	Pilchová, Ivana: 1 article (12/2017)
8.	Račay, Peter: 1 article (12/2017)
9.	Štefaniková, Andrea: 1 article (12/2017)
10.	Guo, Qing: 1 article (07/2017)

Related Diseases

1.	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/01/2017 - "Commentary: SU9516 increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy." 01/01/2017 - "SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy."
2.	Disease Progression 01/01/2017 - "Commentary: SU9516 increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy." 01/01/2017 - "SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy."
3.	Carcinoma (Carcinomatosis) 08/15/2001 - "A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells." 10/01/2002 - "SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells."
4.	Tetraploidy 07/01/2017 - "SU9516 can induce tetraploid blastocyst formation at high efficiency. " 07/01/2017 - "CDK inhibitor SU9516 induces tetraploid blastocyst formation from parthenogenetically activated porcine embryos." 07/01/2017 - "To examine the effect of SU9516, a cyclin-dependent kinase inhibitor, on the induction of tetraploid blastocyst formation in porcine embryos by parthenogenetic activation. "
5.	T-Cell Leukemia (Leukemia, T Cell) 03/01/2010 - "Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell leukemia Jurkat cells."

Related Drugs and Biologics

1.	Integrins
2.	Cyclin-Dependent Kinase 2
3.	Cyclin-Dependent Kinases (cdk Proteins)
4.	Oxindoles
5.	Cytochromes c (Cytochrome c)
6.	Proteins (Proteins, Gene)
7.	Methotrexate (Mexate)
8.	ABT-737