|1.||Hattori, Nobutaka: 5 articles (09/2014 - 08/2007)|
|2.||Cookson, Mark R: 5 articles (09/2014 - 04/2005)|
|3.||Tanaka, Keiji: 4 articles (03/2015 - 10/2010)|
|4.||Matsuda, Noriyuki: 4 articles (03/2015 - 10/2010)|
|5.||Sato, Shigeto: 4 articles (09/2014 - 06/2009)|
|6.||Klein, Christine: 4 articles (01/2013 - 06/2006)|
|7.||Chu, Charleen T: 3 articles (10/2015 - 04/2010)|
|8.||Abramov, Andrey Y: 3 articles (10/2015 - 01/2014)|
|9.||Kimura, Mayumi: 3 articles (03/2015 - 12/2013)|
|10.||Okatsu, Kei: 3 articles (03/2015 - 12/2013)|
|1.||Parkinson Disease (Parkinson's Disease)
02/01/2016 - "Recessive mutations in the PTEN-induced putative kinase 1 (PINK1) gene cause early-onset Parkinson's disease (PD). "
04/20/2015 - "Recessive mutations in PINK1, which encodes the mitochondrially targeted PTEN-induced putative kinase 1 (PINK1), cause an autosomal recessive form of Parkinson's disease. "
02/15/2015 - "Here we show that PTEN-induced putative kinase 1 (PINK1), which is linked to autosomal recessive early-onset familial Parkinson's disease, phosphorylates HDAC3 at Ser-424 to enhance its HDAC activity in a neural cell-specific manner. "
01/01/2015 - "Mutations of the PTEN-induced putative kinase 1 (PINK1) gene are a cause of autosomal recessive forms of Parkinson's disease. "
11/01/2014 - "Recessive mutations in the PTEN-induced putative kinase 1 (PINK1) gene cause early-onset Parkinson's disease (EOPD). "
|2.||Brain Ischemia (Cerebral Ischemia)
05/01/2015 - "Recent studies showed that increased mitochondrial fission is an early event of cell death during cerebral ischemia and dynamin-related protein 1 (Drp1) plays an important role in mitochondrial fission, which may be regulated by PTEN-induced putative kinase 1 (PINK1), a mitochondrial serine/threonine-protein kinase thought to protect cells from stress-induced mitochondrial dysfunction and regulate mitochondrial fission. "
|3.||Parkinsonian Disorders (Parkinsonism)
06/05/2014 - "PINK1 (PTEN induced putative kinase 1) and PARKIN (also known as PARK2) have been identified as the causal genes responsible for hereditary recessive early-onset Parkinsonism. "
05/15/2011 - "We describe recent work suggesting that Parkin and PTEN-induced putative kinase 1 (PINK1), two gene products linked to familial forms of parkinsonism, may constitute one of the cell's mitochondrial quality control pathways-identifying impaired mitochondria and selectively trimming them from the mitochondrial network by mitophagy. "
01/01/2011 - "Mutations in DJ-1, PINK1 (PTEN-induced putative kinase 1) and parkin all cause recessive parkinsonism in humans, but the relationships between these genes are not clearly defined. "
10/01/2010 - "Fortunately, our understanding of the pathogenesis of two types of recessive familial PDs--early-onset familial PD caused by dysfunction of the PTEN induced putative kinase 1 (PINK1) gene and autosomal recessive juvenile Parkinsonism (ARJP) caused by a mutation in the Parkin gene--has evolved and continues to expand."
12/12/2007 - "Mutations in PINK1 (PTEN-induced putative kinase 1) are causal for early onset recessive parkinsonism in humans, characterized by damage to the nigrostriatal system. "
|4.||Colorectal Neoplasms (Colorectal Cancer)
06/01/2015 - "14-3-3ε, 14-3-3 protein epsilon; 3-PGDH, phosphoglycerate dehydrogenase; ALDOA, aldolase A; APT1, acyl-protein thioesterase 1; CaM, calmodulin; CBR3, carbonyl reductase [NADPH] 3; ENO2, gamma-enolase; HPRT, hypoxanthine-guanine phosphoribosyltransferase; HSP70, heat-shock-related 70 kDa protein 2; IDHc, cytoplasmic isocitrate dehydrogenase [NADP+]; MAPK1, mitogen-activated protein kinase 1; MEK1, MAP kinase kinase 1; MDHc, cytoplasmic malate dehydrogenase; NFM, neurofilament medium polypeptide; NSF, N-ethylmaleimide-sensitive fusion protein; PHB, prohibitin; PINK1, PTEN-induced putative kinase 1; PPIaseA, peptidyl-prolyl cis-trans isomerase A; PSA2, proteasome subunit alpha type-2; TK, transketolase; VDAC-2, voltage-dependent anion-selective channel protein 2. "
|2.||Protein Kinases (Protein Kinase)
|6.||Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
|8.||Protein-Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)
|9.||Proteins (Proteins, Gene)