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4- hydroxy- 5,5- dimethyl- 2- trifluoromethylpyrroline- 1- oxide

structure in first source

Also Known As:

FDMPO

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - 4-hydroxy-5,5-dimethyl-2-trifluoromethylpyrroline-1-oxide: 1
- Heterocyclic Oxides
  - Cyclic N-Oxides: 3
    - 4-hydroxy-5,5-dimethyl-2-trifluoromethylpyrroline-1-oxide: 1

Experts

1.	Farzaneh, Shabnam: 1 article (01/2021)
2.	Ghasempour, Mozhgan: 1 article (01/2021)
3.	Khodaparast, Farzad: 1 article (01/2021)
4.	Naserzadeh, Parvaneh: 1 article (01/2021)
5.	Pourahmad, Jalal: 1 article (01/2021)
6.	Salimi, Ahmad: 1 article (01/2021)
7.	Zarghi, Afshin: 1 article (01/2021)

Related Diseases

1.

Melanoma (Melanoma, Malignant)

01/01/2021 - "Our results showed FDMPO could selectively induce cellular and mitochondrial toxicity (up to 50 µM) on melanoma cells and mitochondria without any toxic effects on normal fibroblast and their mitochondria. "
01/01/2021 - "In the present study, we searched selective cytotoxicity and mitochondria mediated apoptosis of novel synthesized chalconeferrocenyl derivative (1-Ferrocenyl-3-(dimethylamino)-3-(4-methylsulfonylphenyl) propan-1-one) (FDMPO) as a COX-2 inhibitor on normal and melanoma cells and their mitochondria. "

Related Drugs and Biologics

1.	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)