|1.||Mruk, Dolores D: 6 articles (02/2013 - 11/2006)|
|2.||Cheng, C Yan: 6 articles (02/2013 - 11/2006)|
|3.||Xia, Weiliang: 5 articles (01/2015 - 01/2013)|
|4.||Silvestrini, Bruno: 5 articles (01/2015 - 11/2006)|
|5.||Zhang, Tingting: 4 articles (01/2015 - 01/2013)|
|6.||Liu, Tengyuan: 4 articles (01/2015 - 01/2013)|
|7.||Shao, Jiaxiang: 3 articles (01/2015 - 01/2013)|
|8.||Yu, Hemei: 2 articles (01/2014 - 01/2013)|
|9.||Xie, Qian Reuben: 2 articles (02/2013 - 01/2013)|
|10.||Wang, Boshi: 2 articles (02/2013 - 01/2013)|
02/01/2012 - "Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility."
10/01/2009 - "Adjudin is known to specifically affect Sertoli-germ cell adhesion, resulting in germ cell loss from the seminiferous epithelium and transient infertility. "
01/01/2009 - "Manipulation of these interactions by drugs like Adjudin can hamper the development of germ cells and lead to conditions of temporary infertility. "
11/01/2006 - "Using this approach, infertility was induced in adult rats when 0.5 microg Adjudin per kg b.w. "
05/01/2001 - "Complete infertility was noted in rats 29 days after the initial dose of AF2364 and continued until 90 days. "
02/01/2013 - "Taken together, these findings have demonstrated that Adjudin may be a potential drug for cancer therapy."
02/01/2013 - "Intraperitoneal administration of Adjudin to tumor-bearing athymic nude mice also significantly suppressed the lung and prostate tumor growth. "
02/01/2013 - "We found that Adjudin induced apoptosis in cancer cells through a Caspase-3-dependent pathway. "
02/01/2013 - "Herein we described the anti-proliferative activity of Adjudin on cancer cells in vitro and on lung and prostate tumors inoculated in nude mice. "
02/01/2013 - "However, whether Adjudin exhibits any anti-cancer activity remains to be elucidated. "
|4.||Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
01/01/2014 - "In this study we continued to explore whether adjudin could be neuroprotective by using the transient middle cerebral artery occlusion (tMCAO) model. "
01/15/2013 - "To determine the in vivo effect of Adjudin, we used a permanent middle cerebral artery occlusion (pMCAO) mouse model and found that Adjudin could reduce ischemia-induced CD11b expression, a marker of microglial activation. "
11/01/2006 - "In a small subset of animals, however, oral administration of Adjudin (50 mg per kg body weight (b.w.) for 29 d) resulted in adverse effects such as liver inflammation and muscle atrophy. "
01/01/2015 - "Recent studies have demonstrated that, besides its activity to induce germ cell exfoliation from the seminiferous epithelium to cause reversible infertility in male rodents, adjudin possesses other biological activities, which include anti-cancer, anti-inflammation in the brain, and anti-ototoxicity induced by gentamicin in rodents. "
|2.||Immunoglobulin G (IgG)
|5.||Adenylate Cyclase (Adenylyl Cyclase)
|6.||Adenosine Triphosphate (ATP)