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acyclo-retinoic acid

an acyclic version of retinoic acid

Also Known As:

acycloretinoic acid

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Nagao, Akihiko: 2 articles (01/2004 - 03/2002)
2.	Kim, Seon-Jae: 1 article (03/2002)
3.	Kobori, Masuko: 1 article (03/2002)
4.	Kotake-Nara, Eiichi: 1 article (03/2002)
5.	Miyashita, Kazuo: 1 article (03/2002)
6.	Ben-Dor, A: 1 article (07/2001)
7.	Danilenko, M: 1 article (07/2001)
8.	Emmerich, T: 1 article (07/2001)
9.	Giat, Y: 1 article (07/2001)
10.	Levy, J: 1 article (07/2001)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 03/01/2002 - "These results showed that acyclo-retinoic acid reduced cell viability by inducing apoptosis in human prostate cancer cells." 03/01/2002 - "Acyclo-retinoic acid induces apoptosis in human prostate cancer cells." 03/01/2002 - "When prostate cancer cells, PC-3, DU 145 and LNCaP, were cultured in a retinoid-supplemented medium, acyclo-retinoic acid remarkably reduced the viability of the cells except for LNCaP. " 03/01/2002 - "The effect of acyclo-retinoic acid on the growth of human prostate cancer cells was compared with those of the four retinoids: all-trans-retinoic acid, geranylgeranoic acid, 9-cis-retinoic acid and N-(4-hydroxyphenyl)retinamide. "
2.	Neoplasms (Cancer) 07/15/2001 - "In summary, acyclo-retinoic acid inhibited cancer cell growth and interacted with RAR. "
3.	Leukemia 01/01/2004 - "We have found that lycopene, a typical nonprovitamin A carotenoid, was cleaved in vitro to acycloretinal, acycloretinoic acid and apolycopenals in a nonenzymatic manner, and that the mixture of oxidation products of lycopene induced apoptosis of HL-60 human promyelocytic leukemia cells. "
4.	Breast Neoplasms (Breast Cancer) 07/15/2001 - "Effects of acyclo-retinoic acid and lycopene on activation of the retinoic acid receptor and proliferation of mammary cancer cells." 07/15/2001 - "The inhibition of human mammary cancer (MCF-7) cell growth and the transactivation of the retinoic acid receptor (RAR) reporter gene by synthetic acyclo-retinoic acid, the open chain analog of retinoic acid, was compared to the effects of lycopene and retinoic acid in the same systems. "

Related Drugs and Biologics

1.	Tretinoin (Retinoic Acid)
2.	Lycopene
3.	Retinoic Acid Receptors (Retinoic Acid Receptor)
4.	Fenretinide
5.	Retinoids
6.	Carotenoids (Carotene)
7.	Alitretinoin
8.	acycloretinal
9.	geranylgeranic acid