LAIR-2 receptor

is expressed on many cells of the immune system and is predicted to mediate inhibitory functions based on the presence of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic domain

Also Known As:

leukocyte-associated immunoglobulin like receptor 2

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        LAIR-2 receptor: 3

Experts

1.	Fallert-Junecko, B: 2 articles (03/2013 - 10/2010)
2.	Founds, S A: 2 articles (03/2013 - 10/2010)
3.	Parks, W T: 2 articles (03/2013 - 10/2010)
4.	Reinhart, T A: 2 articles (03/2013 - 10/2010)
5.	Douwes, Max: 1 article (12/2011)
6.	Meyaard, Linde: 1 article (12/2011)
7.	Olde Nordkamp, Marloes J M: 1 article (12/2011)
8.	Urbanus, Rolf T: 1 article (12/2011)
9.	de Ruiter, Talitha: 1 article (12/2011)
10.	van Roon, Joël A G: 1 article (12/2011)

Related Diseases

1.	Pre-Eclampsia (Preeclampsia) 03/01/2013 - "Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) was identified on a global gene expression microarray analysis of surplus chorionic villus sampling (CVS) tissues as down-regulated in the first trimester of preeclampsia pregnancies. " 10/01/2010 - "A global gene expression microarray analysis of surplus chorionic villus sampling (CVS) tissues identified leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) as down-regulated in the first trimester of pregnancies destined for preeclampsia. "
2.	Rheumatoid Arthritis 12/01/2011 - "Enhanced secretion of leukocyte-associated immunoglobulin-like receptor 2 (LAIR-2) and soluble LAIR-1 in rheumatoid arthritis: LAIR-2 is a more efficient antagonist of the LAIR-1-collagen inhibitory interaction than is soluble LAIR-1."