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AGN 194204

a retinoid X receptor ligand; structure in first source

Also Known As:

AGN-194204; AGN194204; NRX 194204; NRX-194204; NRX194204

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - AGN 194204: 3
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Tetrahydronaphthalenes: 1
        AGN 194204: 3
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - AGN 194204: 3

Experts

1.	Liby, Karen: 2 articles (12/2009 - 10/2007)
2.	Risingsong, Renee: 2 articles (12/2009 - 10/2007)
3.	Royce, Darlene B: 2 articles (12/2009 - 10/2007)
4.	Sporn, Michael B: 2 articles (12/2009 - 10/2007)
5.	Williams, Charlotte R: 2 articles (12/2009 - 10/2007)
6.	Ma, Tian: 1 article (12/2009)
7.	Yore, Mark M: 1 article (12/2009)
8.	Chandraratna, Roshantha A: 1 article (10/2007)
9.	Wood, Matthew D: 1 article (10/2007)
10.	Balasubramanian, Sivaprakasam: 1 article (08/2004)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 08/01/2004 - "In the present study, the novel RXR-selective retinoid, AGN194204, was compared with that of other retinoids for the ability to suppress pancreatic cancer cell proliferation. " 08/01/2004 - "Suppression of human pancreatic cancer cell proliferation by AGN194204, an RXR-selective retinoid."
2.	Carcinogenesis 10/15/2007 - "A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland."
3.	Lung Neoplasms (Lung Cancer) 12/01/2009 - "Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice."
4.	Breast Neoplasms (Breast Cancer) 10/15/2007 - "We evaluated the anti-inflammatory and growth-inhibitory properties of the novel rexinoid NRX194204 (4204) in vitro and then tested its ability to prevent and/or treat experimental lung and estrogen receptor (ER)-negative breast cancer in vivo. "

Related Drugs and Biologics

1.	Retinoids
2.	Triterpenes
3.	Estrogen Receptors
4.	2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid ethyl amide
5.	bardoxolone methyl
6.	LG 100268