monocyte locomotion inhibitory factor

10/01/2012 - "In this study, we further investigated the mechanism underlying the protective role of MLIF in brain ischemia. "
05/01/2011 - "Protective effects of MLIF analogs on cerebral ischemia-reperfusion injury in rats."
08/20/2017 - "New monocyte locomotion inhibitory factor analogs protect against cerebral ischemia-reperfusion injury in rats."
10/01/2012 - "A middle cerebral artery occlusion model in rats was used for detecting the effect of MLIF in the brain ischemia in vivo. "
10/01/2012 - "In this study, we identified a new potential pharmacologically targetable mechanism underlying MLIF's protective effects in brain ischemia through the eEF1A1/endothelial nitric oxide synthase pathway."

01/01/2016 - "These results indicate that MLIF ameliorates OGD-induced SH-SY5Y neuroblastoma injury by inhibiting the p-JNK/p53 apoptotic signaling pathway via eEF1A2. "
01/01/2021 - "Our previous study found that MLIF protects against ischemic stroke in rats and mice and exerts a neuroprotection effect in human neuroblastoma SH-SY5Y cells. "
01/01/2016 - "In this study, we investigated the neuroprotective action of MLIF against oxygen-glucose deprivation (OGD)-induced injury in human neuroblastoma SH-SY5Y cells. "
01/01/2016 - "MLIF Alleviates SH-SY5Y Neuroblastoma Injury Induced by Oxygen-Glucose Deprivation by Targeting Eukaryotic Translation Elongation Factor 1A2."

01/01/2011 - "Microarray data from experimental arthritis revealed an MLIF gene expression profile that includes genes that are involved in apoptosis, cell adhesion, extracellular matrix, and inflammation / chemotaxis. "
12/01/2010 - "MLIF could be an interesting new molecule to investigate in the field of rheumatoid arthritis pathogenesis research for its potential to prevent inflammation."
07/01/1987 - "If active in vivo, MLIF may contribute to the paucity of inflammation in the advanced stages of invasive amebiasis, and consequently to the lack of scar tissue formation upon recovery from such lesions, as monocytes constitute an essential link to the healing process."
09/01/2018 - "MLIF may regulate trauma-induced inflammation through the effects it exerts directly or indirectly on immune cells, modulating the production and/or expression of the cytokines involved in the inflammatory processes that occur after damage. "
09/01/2018 - "The monocyte locomotion inhibitory factor inhibits the expression of inflammation-induced cytokines following experimental contusion in rat tibia."

12/15/2016 - "MLIF improved cell survival and inhibited apoptosis and necrosis by inhibiting the p-JNK and cleaved caspase3 expression. "
01/01/2016 - "We observed that MLIF enhanced cell survival and inhibited apoptosis and necrosis by inhibiting p-JNK, p53, c-caspase9 and c-caspase3 expression. "
09/01/2018 - "Expression levels of the cytokines interferon gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and transforming growth factor-beta (TGF-β) mRNA were inhibited significantly by MLIF at 24 hours post-contusion. "

10/01/2012 - "A middle cerebral artery occlusion model in rats was used for detecting the effect of MLIF in the brain ischemia in vivo. "
01/01/2022 - "In the experimental part, transient middle cerebral artery occlusion (tMCAO) and oxygen and glucose deprivation (OGD) models were used to evaluate the protective efficacy of MLIF and the expression of inflammatory cytokines and the putative targets. "