|1.||Mukhopadhyay, Pralay: 11 articles (07/2015 - 11/2007)|
|2.||Peck, Ronald: 10 articles (02/2012 - 03/2007)|
|3.||Vahdat, Linda T: 8 articles (09/2014 - 08/2007)|
|4.||Vahdat, Linda: 8 articles (08/2012 - 05/2006)|
|5.||Swain, Sandra M: 8 articles (06/2008 - 04/2005)|
|6.||Perez, Edith A: 7 articles (07/2015 - 08/2007)|
|7.||Fojo, Tito: 7 articles (07/2015 - 05/2003)|
|8.||Sparano, Joseph A: 7 articles (10/2013 - 02/2010)|
|9.||Lee, James J: 7 articles (02/2009 - 04/2005)|
|10.||Burris, Howard A: 6 articles (11/2015 - 03/2007)|
|1.||Breast Neoplasms (Breast Cancer)
10/01/2010 - "Ixabepilone, a new treatment option for metastatic breast cancer."
09/01/2008 - "To evaluate the safety and efficacy of ixabepilone as a new antimitotic chemotherapeutic agent for the treatment of breast cancer. "
06/01/2010 - "Efficacy of ixabepilone in ER/PR/HER2-negative (triple-negative) breast cancer."
10/01/2015 - "Phase II Randomized Study of Ixabepilone Versus Observation in Patients With Significant Residual Disease After Neoadjuvant Systemic Therapy for HER2-Negative Breast Cancer."
07/01/2015 - "In this review, we summarized data on pharmacodynamics, pharmacokinetics, preclinical and clinical studies of ixabepilone in breast cancer. "
03/15/2015 - "Subsequent clinical trials established the clinical efficacy of ixabepilone, leading to its regulatory approval for the treatment of drug-resistant metastatic or locally advanced breast cancers."
01/01/2009 - "This study extends previous findings regarding the efficacy of ixabepilone and its low susceptibility to tumor resistance mechanisms and describes the pharmacokinetics of this new antineoplastic agent. "
03/01/2008 - "Ixabepilone represents a new treatment option for MBC patients with cancers resistant to available chemotherapeutic agents."
09/01/2008 - "Phase 1, Phase 2, and Phase 3 clinical trials examining the safety and efficacy of ixabepilone and its place in cancer treatment were reviewed. "
05/01/2014 - "The aim of this study was to establish the maximum tolerated dose (MTD), dose-limiting toxicities (DLTs), safety, and pharmacokinetics (PK) of a novel oral formulation of ixabepilone in patients with advanced solid tumors. "
|3.||Prostatic Neoplasms (Prostate Cancer)
06/01/2012 - "Phase II trial of weekly ixabepilone in men with metastatic castrate-resistant prostate cancer (E3803): a trial of the Eastern Cooperative Oncology Group."
10/01/2003 - "We conducted a dose-escalation study to determine a safe dose of BMS-247550 to combine with EMP in patients with metastatic prostate cancer. "
06/01/2012 - "Here we report the activity and toxicity of ixabepilone, administered by using a weekly schedule, in men with metastatic castrate-resistant prostate cancer (CRPC). "
06/01/2012 - "Here we evaluate the activity of a weekly ixabepilone in men with metastatic castrate-resistant prostate cancer to minimize hematologic toxicity. "
10/01/2003 - "Chemotherapy-naive patients with castrate-metastatic prostate cancer were treated with intravenous BMS-247550 and oral EMP (280 mg three times daily for 5 days) every 3 weeks. "
|4.||Pancreatic Neoplasms (Pancreatic Cancer)
01/01/2014 - "Although these trials are promising with regard to addition of ixabepilone to the slim armamentarium for management of pancreatic cancer, further work is still to be done. "
01/01/2014 - "Importantly, this work bears the burden of not only validating the clinical benefit of ixabepilone, but also of determining whether this benefit is enhanced in any way by combination therapy, and where ixabepilone fits in the sequence of management for patients with metastatic pancreatic cancer. "
01/01/2014 - "Profile and potential of ixabepilone in the treatment of pancreatic cancer."
11/01/2006 - "Ixabepilone shows encouraging activity in patients with advanced pancreatic cancer and should be investigated further in this disease."
09/01/2012 - "The aim of this phase 2 study was to evaluate the safety and efficacy of ixabepilone plus cetuximab in patients with advanced pancreatic cancer. "
|5.||Endometrial Neoplasms (Endometrial Cancer)
07/01/2009 - "Phase II trial of ixabepilone as second-line treatment in advanced endometrial cancer: gynecologic oncology group trial 129-P."
07/01/2009 - "CONCLUSION In a cohort of women with advanced or recurrent endometrial cancer who were previously treated with paclitaxel, ixabepilone showed modest activity of limited duration as a second-line agent."
07/01/2015 - "Phase III randomized trial of second-line ixabepilone versus paclitaxel or doxorubicin in women with advanced endometrial cancer."
07/01/2009 - "PURPOSE A phase II study was conducted to determine the response rate of ixabepilone (BMS-247550, National Cancer Institute (NCI)-supplied agent investigational new drug No. 59,699) in patients with persistent or recurrent endometrial cancer who have progressed despite standard therapy. "
07/01/2015 - "The purpose of this multicenter, open label, randomized phase III study was to determine whether ixabepilone resulted in improved overall survival (OS) compared with commonly used single-agent chemotherapy (doxorubicin or paclitaxel) in women with locally advanced, recurrent, or metastatic endometrial cancer with at least one failed prior platinum-based chemotherapeutic regimen. "
|4.||epothilone B (EPO906)
|1.||Drug Therapy (Chemotherapy)