prostatic acid phosphatase

Also Known As:

ACP-3 protein, human; ACP3 protein, human; ACPP protein, human; Acpp protein, mouse; Acpp protein, rat; Acpp11 protein, rat; acid phosphatase, prostate, human; acid phosphatase, prostate, mouse; acid phosphatase, prostate, rat; prostatic-specific acid phosphatase

Networked: 773 relevant articles (21 outcomes, 63 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Phosphoric Monoester Hydrolases: 7477
        Acid Phosphatase: 2344
        prostatic acid phosphatase: 773

Experts

1.	McNeel, Douglas G: 13 articles (01/2020 - 12/2005)
2.	Johnson, Laura E: 10 articles (12/2019 - 01/2006)
3.	Lin, Ming-Fong: 9 articles (10/2021 - 02/2003)
4.	Fong, Lawrence: 7 articles (01/2021 - 10/2003)
5.	Small, Eric J: 7 articles (08/2015 - 10/2003)
6.	Drake, Charles G: 6 articles (01/2021 - 05/2010)
7.	Antonarakis, Emmanuel S: 5 articles (10/2021 - 05/2010)
8.	Liu, Glenn: 5 articles (12/2019 - 12/2005)
9.	Vihko, Pirkko: 5 articles (01/2019 - 10/2008)
10.	Lin, Fen-Fen: 5 articles (01/2015 - 02/2003)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 07/01/1983 - "We compared a commercial radioimmunoassay kit with an enzymatic assay for prostatic acid phosphatase in monitoring the progression or remission of disease in 27 patients with prostatic cancer. " 08/01/1981 - "[Improved diagnostic evaluation of prostatic neoplasms using radioimmunoassay for prostatic acid phosphatase]." 01/01/2019 - "Prostatic Acid Phosphatase (PAP) Predicts Prostate Cancer Progress in a Population-Based Study: The Renewal of PAP?" 01/01/1992 - "In this study twenty male urethral specimens were evaluated for PSA and prostatic acid phosphatase (PAP) from patients without evidence of prostatic cancer. " 01/01/1979 - "A national study of the new specific assays for prostatic acid phosphatase was conducted by the National Prostatic Cancer Project. "
2.	Neoplasms (Cancer) 06/01/1983 - "No major adverse effects were noted with this treatment modality, and all patients were symptomatically improved and demonstrated a decrease or stabilization in tumor activity as measured by prostatic computerized tomography or ultrasound scan, prostatic acid phosphatase and bone scan. " 04/01/1999 - "On the basis of this blinded study, RT-PCR for PSA-expressing cells in 85 patients before RP is not related to clinical stage, age, race, grade, Gleason sum, serum PSA or prostatic acid phosphatase, tumor volume, or tumor multifocality. " 10/04/2021 - "Multifunctionality of Prostatic Acid Phosphatase in Prostate Cancer Pathogenesis." 09/01/2015 - "Our results document the suppression of subcutaneous tumor growth in animals immunized with AAV6-S663V+T492V vectors expressing prostatic acid phosphatase (PAP) for approximately 4 weeks in comparison with 1 week and 2 weeks for the negative controls, AAV6-EGFP, and AAV6-WT-PAP treated mice, respectively. " 08/01/2014 - "Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor."
3.	Carcinoma (Carcinomatosis) 02/15/2003 - "The objective of this study was to define the long-term prognostic significance of prostatic acid phosphatase (PAP) levels in patients with higher risk, early-stage prostate carcinoma. " 06/01/2002 - "The level of prostatic acid phosphatase in serum is an established marker for prostate carcinoma. " 11/01/1999 - "Prognostic role of serum prostatic acid phosphatase for 103Pd-based radiation for prostatic carcinoma." 05/01/1996 - "The histological and gross findings of the prostate were correlated with premortem prostatic acid phosphatase levels (PAP, enzymatic method, ACA, Dupont Co.) to determine how often carcinoma of the prostate (CAP) affected PAP levels and to identify other findings within the prostate associated with elevated PAP levels. " 04/28/1995 - "The expression of prostatic acid phosphatase is transcriptionally regulated in human prostate carcinoma cells."
4.	Adenocarcinoma 05/01/1985 - "Furthermore, under electron microscopic study, prostatic specific acid phosphatase granules were uniformly and intensely condensed in intracytoplasmic vacuoles in well differentiated adenocarcinomas, whereas in moderately or poorly differentiated adenocarcinomas 2 types of staining were observed. " 03/01/1980 - "Results of such a study show an increased diagnostic sensitivity of the radioimmunoassay in all stages, but in 14% of Stage IV adenocarcinomas there was no increase in prostatic acid phosphatase above the ranges ordinarily expected for all methods. " 12/25/2020 - "Permanent pathology with stains were positive for PSA and prostatic-specific acid phosphatase (PSAP), making the diagnosis of metastatic prostate adenocarcinoma. " 02/01/2016 - "We have previously shown in a murine model that prostatic acid phosphatase (PAP) deficiency leads to increased cell proliferation and development of prostate adenocarcinoma. " 01/01/2013 - "Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma."
5.	Disease Progression 01/01/1983 - "Changes of the radioimmunologically determined prostatic acid phosphatase seemed most often to indicate the presence of advanced disease and subsequent disease progression. " 01/01/2019 - "To characterize the disease progression and median survival of patients with prostate cancer (PCa) according to the prostatic-specific acid phosphatase (PAP) analysis in a population-based study from the Surveillance, Epidemiology, and End Results (SEER) database. " 11/01/1986 - "The clinical course of 25 patients with clinical stage C adenocarcinoma of the prostate who had pre-treatment elevations of the prostatic acid phosphatase (Roy test) was analyzed retrospectively. " 09/01/1994 - "Prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) are the tumor markers for monitoring disease progression or improvement in patients with prostate adenocarcinoma. " 05/01/1990 - "[Studies on relationship between histology, tumor markers (prostatic acid phosphatase.prostate specific antigen.gamma-seminoprotein.leu-7) and clinical course in prostate cancer]."

Related Drugs and Biologics

1.	Antigens
2.	Prostate-Specific Antigen (Semenogelase)
3.	sipuleucel-T (APC8015)
4.	Vaccines
5.	Tumor Biomarkers (Tumor Markers)
6.	Biomarkers (Surrogate Marker)
7.	Alkaline Phosphatase
8.	Proteins (Proteins, Gene)
9.	A-Form DNA (A-DNA)
10.	Androgens

Related Therapies and Procedures

1.	Immunotherapy
2.	Therapeutics
3.	Aftercare (After-Treatment)
4.	Castration
5.	Prostatectomy (Retropubic Prostatectomy)