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mappain
from Macaranga mappa; structure in first source
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzylidene Compounds: 10
Stilbenes: 657
mappain: 1
Experts
1.
Hemscheidt, T K
: 1 article (01/2001)
2.
Mooberry, S L
: 1 article (01/2001)
3.
van Der Kaaden, J E
: 1 article (01/2001)
Related Diseases
1.
Ovarian Neoplasms (Ovarian Cancer)
01/01/2001 - "
Mappain is cytotoxic but it appears to be a poor substrate for P-glycoprotein-mediated transport because it is equally potent and effective against the drug-sensitive SK-OV-3 and drug-resistant SKVLB-1 ovarian cancer cell lines, exhibiting an IC(50) value of 1.3 microM in both cases.
"
Related Drugs and Biologics
1.
Member 1 Subfamily B ATP Binding Cassette Transporter