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2- (3- estrone- N- ethyl- piperazine- methyl)tetracycline

structure in first source

Also Known As:

XW630

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - 2-(3-estrone-N-ethyl-piperazine-methyl)tetracycline: 3
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        Tetracyclines: 1162
        2-(3-estrone-N-ethyl-piperazine-methyl)tetracycline: 3
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - Tetracyclines: 1162
      - 2-(3-estrone-N-ethyl-piperazine-methyl)tetracycline: 3

Experts

1.	Deng, Li: 1 article (06/2003)
2.	Fei, Wei: 1 article (06/2003)
3.	Wang, Dazhang: 1 article (06/2003)
4.	Weng, Lingling: 1 article (06/2003)
5.	Zheng, Hu: 1 article (06/2003)
6.	Liu, J S: 1 article (03/2000)
7.	Qiu, M C: 1 article (03/2000)
8.	Sun, L: 1 article (03/2000)
9.	Weng, L L: 1 article (03/2000)
10.	Zheng, H: 1 article (03/2000)

Related Diseases

1.	Osteoporosis 06/01/2003 - "This study was performed to investigate the mechanism of an anti-osteoporosis new drug XW630 for promoting the osteogenic action. " 03/01/2000 - "To study the effects of 2-[3-estrone-N-ethyl-piperazine-methyl]tetracycline (XW630) on experimental osteoporosis in ovariectomized (OVX) rats. " 03/01/2000 - "Effects of 2-[3-estrone-N-ethyl-piperazine-methyl]tetracycline (XW630) on osteoporosis in ovariectomized rats." 09/01/1998 - "[The estrogenic activities of 2-[3-estrone-N-ethyl-piperazine-methyl]tetracycline(XW630)--a new compound with anti-osteoporosis activity]." 09/01/1998 - "2-[3-Estrone-N-ethyl-piperazine-methyl] tetracycline (XW630) showing anti-osteoporosis activity is a new compound with piperazine-tetracycline in the steroid structure of estrone. "
2.	Myoma 09/01/1998 - "The relative affinities of estrone, estradiol and XW630 with estrogen receptor (ER) of the uterine myoma tissues were found to be 0.325, 1.000 and 0.011, respectively, by the competitive assay. "
3.	Bone Resorption 03/01/2000 - "XW630 stimulated bone formation and inhibited bone resorption with no effect on reproductive system."

Related Drugs and Biologics

1.	Tetracycline (Achromycin)
2.	Estrone
3.	Piperazine
4.	Steroids
5.	Estrogen Receptors
6.	Estradiol (Delestrogen)