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DP-109

structure in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Diamines: 518
      - Ethylenediamines: 7
        Egtazic Acid: 365
        DP-109: 4
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Egtazic Acid: 365
        DP-109: 4

Experts

1.	Friedman, Jonathan E: 2 articles (08/2007 - 11/2004)
2.	Angel, Itzchak: 2 articles (09/2005 - 11/2004)
3.	Alsaied, Osama A: 1 article (08/2007)
4.	Baranova, Oxana: 1 article (08/2007)
5.	Beal, M Flint: 1 article (08/2007)
6.	Calingasan, Noel Y: 1 article (08/2007)
7.	Chavez, Juan C: 1 article (08/2007)
8.	Kiaei, Mahmoud: 1 article (08/2007)
9.	Petri, Susanne: 1 article (08/2007)
10.	Wille, Elizabeth: 1 article (08/2007)

Related Diseases

1.	Amyloid Plaque 11/01/2004 - "Daily gavage administration of DP-109 for 3 months markedly reduced the burden of amyloid plaques and the degree of cerebral amyloid angiopathy in brains, compared to animals receiving vehicle treatment. "
2.	Neurodegenerative Diseases (Neurodegenerative Disease) 09/13/2005 - "DP-109, a lipophilic bivalent metal ion modulator currently under preclinical development for neurodegenerative disorders, was designed to have membrane-associated activity, thereby restricting its action to the vicinity of cell membranes. "
3.	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 11/01/2004 - "Daily gavage administration of DP-109 for 3 months markedly reduced the burden of amyloid plaques and the degree of cerebral amyloid angiopathy in brains, compared to animals receiving vehicle treatment. "
4.	Brain Diseases (Brain Disorder) 03/01/2001 - "The new approach to drug development, especially for cardiovascular and brain diseases, brought to synthesis of new lipophillic derivatives of strong calcium chelator BAPTA - DP-b99 and DP-109. "
5.	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 08/01/2007 - "The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis."

Related Drugs and Biologics

1.	Metals
2.	Calcium Chelating Agents
3.	Chelating Agents
4.	DP 460
5.	DP-b99
6.	1,2- bis(2- aminophenoxy)ethane- N,N,N',N'- tetraacetic acid (BAPTA)