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tarchonanthuslactone

structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Pyrones: 35
      - tarchonanthuslactone: 2

Experts

1.	Barbosa Trivella, Daniela Barreto: 1 article (10/2015)
2.	Ernesto de Carvalho, João: 1 article (10/2015)
3.	Ferreira-Halder, Carmen Veríssima: 1 article (10/2015)
4.	Martins Avila, Carolina: 1 article (10/2015)
5.	Pelizzaro-Rocha, Karin Juliane: 1 article (10/2015)
6.	Pereira Dias, Marina: 1 article (10/2015)
7.	Pilli, Ronaldo Aloise: 1 article (10/2015)
8.	Toneto Novaes, Luiz Fernando: 1 article (10/2015)
9.	Vendramini-Costa, Débora Barbosa: 1 article (10/2015)
10.	Avila, Carolina M: 1 article (03/2015)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2015 - "(-)-Tarchonanthuslactone: Design of New Analogues, Evaluation of their Antiproliferative Activity on Cancer Cell Lines, and Preliminary Mechanistic Studies." 10/01/2015 - "Dihydropyran-2-one 8 [(S,E)-(6-oxo-3,6-dihydro-2H-pyran-2-yl)methyl 3-(3,4-dihydroxyphenyl)acrylate], a simplified analogue of (-)-tarchonanthuslactone (1) bearing an additional electrophilic site and a catechol system, was the most cytotoxic and selective compound against six of the eight cancer cell lines analyzed, including the pancreatic cancer cell line. "
2.	Pancreatic Neoplasms (Pancreatic Cancer) 10/01/2015 - "Dihydropyran-2-one 8 [(S,E)-(6-oxo-3,6-dihydro-2H-pyran-2-yl)methyl 3-(3,4-dihydroxyphenyl)acrylate], a simplified analogue of (-)-tarchonanthuslactone (1) bearing an additional electrophilic site and a catechol system, was the most cytotoxic and selective compound against six of the eight cancer cell lines analyzed, including the pancreatic cancer cell line. "
3.	Obesity 03/19/2015 - "Here, we report that, in opposition to the common sense, tarchonanthuslactone has a glucose-increasing effect in a mouse model of obesity and type 2 diabetes mellitus. "
4.	Type 2 Diabetes Mellitus (MODY) 03/19/2015 - "(-)-Tarchonanthuslactone exerts a blood glucose-increasing effect in experimental type 2 diabetes mellitus." 03/19/2015 - "Here, we report that, in opposition to the common sense, tarchonanthuslactone has a glucose-increasing effect in a mouse model of obesity and type 2 diabetes mellitus. "

Related Drugs and Biologics

1.	Pyrans
2.	Glucose (Dextrose)
3.	Blood Glucose (Blood Sugar)
4.	acrylic acid (acrylate)
5.	catechol (pyrocatechol)