|1.||Jiang, Wen G: 8 articles (04/2013 - 09/2004)|
|2.||Kijima, H: 6 articles (10/2001 - 01/2000)|
|3.||Fukuda, Noboru: 5 articles (03/2007 - 01/2003)|
|4.||Mason, Malcolm D: 4 articles (07/2008 - 09/2004)|
|5.||Saito, Satoshi: 4 articles (03/2007 - 01/2003)|
|6.||Matsumoto, Koichi: 4 articles (03/2007 - 01/2004)|
|7.||Kijima, Hiroshi: 4 articles (06/2004 - 06/2002)|
|8.||Ueyama, Yoshito: 4 articles (06/2004 - 06/2002)|
|9.||Scanlon, K J: 4 articles (10/2001 - 01/2000)|
|10.||Yamazaki, H: 4 articles (08/2001 - 09/2000)|
07/01/2002 - "To overcome the BCRP-mediated drug resistance, a specific anti-BCRP hammerhead ribozyme was introduced into the human gastric carcinoma cell line, EPG85-257RNOV, exhibiting an atypical MDR phenotype. "
02/01/2001 - "Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma."
01/01/1997 - "Modulation of c-fms proto-oncogene in an ovarian carcinoma cell line by a hammerhead ribozyme."
01/01/2000 - "We evaluated the efficacy of an anti-K-ras hammerhead ribozyme targeted against GUU-mutated codon 12 of the K-ras gene in cultured pancreatic carcinoma cell lines. "
12/18/1998 - "We have evaluated the efficacy of an anti-K-ras hammerhead ribozyme targeted against GUU-mutated codon 12 of the K-ras gene in a cell-free system as well as in cultured pancreatic carcinoma cell lines. "
10/01/2007 - "We reduced the expression of this molecule in both PC-3 and DU-145 cell lines using hammerhead ribozyme technology, and we examined various important characteristics associated with cancer progression and development in vitro. "
05/01/2007 - "Phi29 pRNA vector for efficient escort of hammerhead ribozyme targeting survivin in multiple cancer cells."
05/01/2005 - "Expression cassettes of human SDF-1 and hammerhead ribozyme transgenes specifically targeting human SDF-1 were constructed and used to over-express SDF-1 or to knockout the expression of SDF-1 in cancer cells, respectively. "
06/01/2002 - "Thus, hammerhead ribozyme against gamma-GCS is suggested to have potential as a cancer gene therapy to reduce the resistance of malignant cells to ionizing radiation and anti-cancer drugs."
08/19/1994 - "To assess the role of PTN in tumor growth, we inactivated the PTN gene with PTN-targeted hammerhead ribozyme constructs. "
|3.||Breast Neoplasms (Breast Cancer)
03/01/2010 - "In this study, we attempt to reverse the malignant phenotype of the breast cancer cell line, MCF-7, using a HER-2-specific hammerhead ribozyme. "
08/01/2001 - "This study examined a transgene-consisting of a combination of U1snRNA, hammerhead ribozyme, and antisense, designed to inhibit c-met expression-and its impact on the migration and in vitro invasion of breast cancer cells. "
04/01/2013 - "We knocked-down the expression of AAMP through transfection of MCF-7 and MDA-MB-231 breast cancer cells with a hammerhead ribozyme transgene (MCF-7(AAMPrib) and MDA-MB-231(AAMPrib)) and examined the impact on cell function using in vitro assays. "
11/01/2010 - "We first constructed a hammerhead ribozyme transgene to knock down Ehm2 expression in breast cancer cells. "
08/01/2001 - "These data show that targeting c-MET by way of a hammerhead ribozyme encoding antisense to c-MET is an effective approach in reducing the invasiveness of breast cancer cells."
|5.||Urinary Bladder Neoplasms (Bladder Cancer)
|2.||Messenger RNA (mRNA)
|3.||Proliferating Cell Nuclear Antigen (PCNA)
|5.||Matrix Metalloproteinase 7 (Matrilysin)
|6.||Telomerase (Telomerase Reverse Transcriptase)
|7.||Catalytic RNA (Ribozymes)
|8.||Androgen Receptors (Androgen Receptor)
|9.||Protein Kinases (Protein Kinase)
|10.||Apolipoproteins B (ApoB)
|1.||Bone Marrow Purging
|2.||Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)
|3.||Heterologous Transplantation (Xenotransplantation)