UCS15A

from Streptomyces; structure in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Kimura, Ken-Ichi: 1 article (01/2010)
2.	Takahashi, Hidetoshi: 1 article (01/2010)
3.	Tsuchiya, Eiko: 1 article (01/2010)
4.	Ueno, Masaru: 1 article (01/2010)
5.	Yukawa, Masashi: 1 article (01/2010)
6.	Atatreh, Noor: 1 article (10/2007)
7.	Barraclough, Jane: 1 article (10/2007)
8.	Bryce, Richard A: 1 article (10/2007)
9.	Cawthorne, Christopher: 1 article (10/2007)
10.	Dive, Caroline: 1 article (10/2007)

1.	Colorectal Neoplasms (Colorectal Cancer) 10/01/2007 - "Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells."
2.	Neoplasms (Cancer) 01/01/2010 - "We performed screening on culture broth of various microbes, and identified five compounds, borrelidin, mycophenolic acid, UCS15A, copiamycin analog, and fredericamycin A, that were known to possess anti-tumor activity. "
3.	Neoplasm Metastasis (Metastasis) 05/02/2006 - "We also found that a small-molecule compound, UCS15A, which was previously judged as a weak inhibitor against canonical SH3/proline bindings, effectively inhibits AMAP1/cortactin binding and breast cancer invasion and metastasis. "
4.	Breast Neoplasms (Breast Cancer) 05/02/2006 - "We also found that a small-molecule compound, UCS15A, which was previously judged as a weak inhibitor against canonical SH3/proline bindings, effectively inhibits AMAP1/cortactin binding and breast cancer invasion and metastasis. "
5.	Bone Resorption 04/19/2001 - "One of the biological consequences of src-inhibition by UCS15A was its ability to inhibit the bone resorption activity of osteoclasts in vitro. " 04/19/2001 - "These data suggest that UCS15A may inhibit the bone resorption activity of osteoclasts, not by inhibiting src tyrosine kinase activity, but by disrupting the interaction of proteins associated with src, thereby modulating downstream events in the src signal transduction pathway."