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human TEL-ARG fusion protein

human fusion protein reported in patients with chronic myeloid leukemia was engineered and expressed in mice; formed by t(1;12)(q25;p13) reciprocal translocation, which fuses part of the TEL gene to the tyrosine kinase; TEL/ARG-transfected Ba/F3 cells with IL-3 completely prevented STI571-induced apoptosis
Also Known As:
TEL-ARG fusion protein, human; TEL-ARG protein, human
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