|1.||Salvemini, Daniela: 5 articles (10/2004 - 01/2003)|
|2.||Mollace, Vincenzo: 2 articles (10/2004 - 06/2003)|
|3.||Palma, Ernesto: 2 articles (10/2004 - 06/2003)|
|4.||Muscoli, Carolina: 2 articles (10/2004 - 06/2003)|
|5.||Nisticò, Robert: 2 articles (10/2004 - 06/2003)|
|6.||Rotiroti, Domenicantonio: 2 articles (10/2004 - 06/2003)|
|7.||Mazzon, Emanuela: 2 articles (09/2004 - 01/2004)|
|8.||Cuzzocrea, Salvatore: 2 articles (09/2004 - 01/2004)|
|9.||Genovese, Tiziana: 2 articles (09/2004 - 01/2004)|
|10.||Di Paola, Rosanna: 2 articles (09/2004 - 01/2004)|
01/01/2001 - "2. Treatment of rats with M40401 (applied at 0.25, 2.5 or 25 microg kg(-1), 15 min prior to reperfusion), attenuated the mean arterial blood and the migration of polymorphonuclear cells (PMNs) caused by SAO-shock. "
01/01/2004 - "This study provides the first evidence that M40401 attenuates the degree of zymosan-induced nonseptic shock in the rat."
01/01/2004 - "We investigated the effects of M40401 on the organ failure associated with nonseptic shock caused by zymosan (500 mg/kg, administered intraperitoneally as a suspension in saline) in rats. "
01/01/2003 - "coli lipopolysaccharide (4 mg/kg) challenged anesthetized rat model of shock, we demonstrated that the vasoconstrictor ability of norepinephrine was indeed restored after M40401 treatment (25 microg/kg). "
01/01/2001 - "Here we have investigated the effects of M40401, a new S:,S:-dimethyl substituted biscyclohexylpyridine Mn-based superoxide dismutase mimetic (SODm, k(cat)=1.2x10(+9) M(-1) s(-1) at pH=7.4), in rats subjected to SAO shock. "
06/16/2003 - "Taken together, these results demonstrate that M40401 provides protective effects when given early after the induction of ischemia-reperfusion of brain tissues and suggest the possible use of such compounds in the treatment of neurological dysfunction subsequent to cerebral flow disturbances."
06/16/2003 - "The protective effect of M40401 was associated with a significant reduction of the levels of malondialdehyde (MDA; a marker of lipid peroxidation) in ischemic brain tissues after ischemia-reperfusion. "
07/31/2003 - "We investigated the effects of two new low molecular weight nonpeptidyl superoxide dismutase (SOD) mimetics (M40403/M40401; MetaPhore Pharmaceuticals) on infarct volume after hypoxia-ischemia injury (H/I) in immature rats. "
|3.||Brain Injuries (Brain Injury)
06/16/2003 - "In animals undergoing ischemia-reperfusion injury, neuropathological and ultrastructural changes were monitored for 1-7 days either in the presence or in the absence of M40401 after bilateral common carotid artery occlusion (BCCO). "
06/16/2003 - "Here we studied the effect of a low molecular weight superoxide dismutase mimetic (M40401) in brain damage subsequent to ischemia-reperfusion injury in Mongolian gerbils. "
10/27/2004 - "Superoxide dismutase mimetic m40401 reduces ischemia-reperfusion injury and graft coronary artery disease in rodent cardiac allografts."
|6.||Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)
|7.||Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
|8.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
|2.||Homologous Transplantation (Allograft)