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(2-boronoethyl)-cysteine

a slow-binding competitive inhibitor of the manganese metalloenzyme arginase; structure in first source

Also Known As:

S-(2-boronoethyl)-L-cysteine

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Acids: 53217
  - Noncarboxylic Acids
    - Boronic Acids: 200
      - (2-boronoethyl)-cysteine: 5
- Boron Compounds: 91
  - Boronic Acids: 200
    - (2-boronoethyl)-cysteine: 5
Organic Chemicals: 133
- Boron Compounds: 91
  - Boronic Acids: 200
    - (2-boronoethyl)-cysteine: 5

Experts

1.	Bocklage, Therese J: 1 article (01/2021)
2.	Feola, David J: 1 article (01/2021)
3.	Garneau-Tsodikova, Sylvie: 1 article (01/2021)
4.	Garvy, Beth A: 1 article (01/2021)
5.	Gonzalez, Rene: 1 article (01/2021)
6.	Haydar, Dalia: 1 article (01/2021)
7.	Thamban Chandrika, Nishad: 1 article (01/2021)
8.	Awad, Alaa S: 1 article (11/2011)
9.	Cooper, Timothy K: 1 article (11/2011)
10.	Gao, Ting: 1 article (11/2011)

Related Diseases

1.	Neointima 04/01/2009 - "Furthermore, local perivascular application of the potent and selective arginase inhibitors S-(2-boronoethyl)-L-cysteine (BEC) or N(G)-hydroxy-nor-L-arginine (L-OHNA) immediately after injury markedly attenuated medial and neointimal DNA synthesis and neointima formation. "
2.	Weight Loss (Weight Reduction) 01/01/2021 - "Conversely, treatment of BALB/c mice with the arginase inhibitor S-(2-boronoethyl)-l-cysteine hydrochloride (BEC) did not change morbidity as defined by weight loss, but mice at day 10 post-infection treated with BEC had gained significantly more weight back than controls. "
3.	Neoplasms (Cancer) 11/22/2022 - "Animal experiments demonstrated that, at 16 h post injection, the fluorescence imaging signal of Cy5.5-CBT-NPs showed a 3.1-fold increase on the tumor sites of mice treated by an immune-activating drug S-(2-boronoethyl)-L-cysteine hydrochloride. "
4.	Infections 01/01/2021 - "Conversely, treatment of BALB/c mice with the arginase inhibitor S-(2-boronoethyl)-l-cysteine hydrochloride (BEC) did not change morbidity as defined by weight loss, but mice at day 10 post-infection treated with BEC had gained significantly more weight back than controls. "
5.	Colitis 08/01/2004 - "Treatment with the arginase inhibitor S-(2-boronoethyl)-l-cysteine worsened colitis in both wild-type and iNOS(-/-) mice. "

Related Drugs and Biologics

1.	Arginase
2.	DNA (Deoxyribonucleic Acid)
3.	Arginine (L-Arginine)