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NS 3623

structure in first source

Also Known As:

NS3623

Networked: 3 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Phenylurea Compounds: 1
      - NS 3623: 3
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenylurea Compounds: 1
        NS 3623: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Tetrazoles: 14
      - NS 3623: 3

Experts

1.	Cannell, Mark B: 1 article (01/2018)
2.	Doray, Adélaïde: 1 article (01/2018)
3.	Hancox, Jules C: 1 article (01/2018)
4.	Lainez, Sergio: 1 article (01/2018)
5.	Grunnet, Morten: 1 article (06/2007)
6.	Hansen, Rie Schultz: 1 article (06/2007)
7.	Olesen, Søren-Peter: 1 article (06/2007)
8.	Asakura, T: 1 article (03/2001)
9.	Bennekou, P: 1 article (03/2001)
10.	Brugnara, C: 1 article (03/2001)

Related Diseases

1.	Dehydration (Water Stress) 03/01/2001 - "Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease." 03/01/2001 - "To study whether Cl-conductance block might prevent dehydration of sickle RBCs, a novel Cl-conductance inhibitor (NS3623) was characterized in vitro using RBCs from healthy donors and sickle cell patients and in vivo using normal mice and a transgenic mouse model of sickle cell disease (SAD mice). "
2.	Sickle Cell Anemia (Hemoglobin S Disease) 03/01/2001 - "Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease." 03/01/2001 - "To study whether Cl-conductance block might prevent dehydration of sickle RBCs, a novel Cl-conductance inhibitor (NS3623) was characterized in vitro using RBCs from healthy donors and sickle cell patients and in vivo using normal mice and a transgenic mouse model of sickle cell disease (SAD mice). "
3.	Heart Failure 01/01/2018 - "A dual Ito and IKr activator, NS3623, has been recently proposed to be beneficial in heart failure and the action of NS3623 on the two channels was also investigated. "
4.	Premature Cardiac Complexes (Extrasystoles) 06/01/2007 - "NS3623 decreased QT variability and distinctly decreased the occurrence of extrasystoles in the acutely bradypaced hearts. "