Biafine

09/01/2004 - "Information about Biafine for radiation dermatitis excluded important information."
12/01/2000 - "Using the RTOG toxicity scale there was no overall difference for maximum dermatitis during RT between Biafine and BSC (p = 0.77). "
12/01/2018 - "This study showed no difference between Mebo and Biafine in the incidence and severity of breast skin dermatitis during radiation therapy. "
09/01/2001 - "To assess the efficacy of Biafine cream in preventing Grade 2 acute radiation dermatitis, according to the National Cancer Institute of Canada skin radiation toxicity criteria in patients undergoing concomitant adjuvant chemotherapy and radiotherapy to the breast. "
03/01/2001 - "Topical Biafine and Lipiderm for the prevention of radiation dermatitis: a randomized prospective trial."

09/01/2020 - "Mepitel Film is superior to Biafine cream in managing acute radiation-induced skin reactions in head and neck cancer patients: a randomised intra-patient controlled clinical trial."
09/01/2020 - "In the current study, we compared the effect of Mepitel Film and Biafine cream on skin reaction severity in a larger cohort of head and neck cancer patients. "

12/01/2000 - "To determine if Biafine compared to Best Supportive Care (BSC) is effective in minimizing or preventing radiation-induced dermatitis in women undergoing breast irradiation. "
12/01/2000 - "There was no overall difference between BSC and Biafine in the prevention, time to, or duration of radiation-induced dermatitis."

01/01/1997 - "Biafine applied on human epidermal wounds is chemotactic for macrophages and increases the IL-1/IL-6 ratio."
11/01/2007 - "In clinical trials, the use of Biafine, a topical emulsion, promoted wound healing following these clinical situations by increasing the number of macrophages recruited to a wound and thus enhancing healing. "
09/01/2015 - "Biafine treatment accelerated wound closure clinically, with greater epidermal/dermal maturity, granulation tissue formation, and collagen quality and arrangement compared to other groups histologically. "
09/01/2015 - "It was previously suggested that the mechanism by which Biafine topical emulsion improves wound healing is via enhanced macrophage infiltration into the wound bed. "
09/01/2015 - "In conclusion, Biafine can be considered an alternative topical therapy for full-thickness excisional and burn wounds, owing to its advantageous biologically based wound healing properties."

09/01/2015 - "In the burn arm, mice were divided into untreated control, Biafine, and SSD groups. "
09/01/2015 - "Biafine topical emulsion accelerates excisional and burn wound healing in mice."
04/01/2004 - "Partial-thickness porcine burns treated with SSD, biafine, and soaked saline gauze re-epithelialize at similar rates."
04/01/2004 - "The decreases in burn area from day 2 to day 12 were 21.4 cm(2) (+/-6.0 cm(2)) in pigs treated with biafine, 20.0 cm(2) (+/-6.3 cm(2)) in pigs treated with SSD, and 19.8 cm(2) (+/-5.9 cm(2)) in pigs treated with saline-soaked gauze (p = NS). "
04/01/2004 - "Time to re-epithelialization of the burns was 13.5 days (SD +/- 0.9 days) in pigs treated with biafine, 13.3 days (+/-1.3 days) in pigs treated with SSD, and 13.5 days (+/-1.0 days) in pigs treated with saline-soaked gauze (p = not significant [NS]). "