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BMS 189453

structure in first source

Also Known As:

BMS-189453

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Businaro, Rita: 1 article (05/2017)
2.	Cipollone, Daria: 1 article (05/2017)
3.	Cozzi, Denis A: 1 article (05/2017)
4.	Marino, Bruno: 1 article (05/2017)
5.	Hunter, Edward Sidney: 1 article (09/2007)
6.	Johnson, Corey S: 1 article (09/2007)
7.	Sulik, Kathleen K: 1 article (09/2007)
8.	Zucker, Robert M: 1 article (09/2007)
9.	Beehler, Blake C: 1 article (02/2003)
10.	Chen, Simon: 1 article (02/2003)

Related Diseases

1.	Disease Progression 02/01/2003 - "BMS-189453 treatment blocked the clinical progression of arthritis beyond soft tissue inflammation in the CIA model. " 02/01/2003 - "Improvement in clinical and histologic variables in 2 separate animal models, along with simultaneous reduction in MMP expression in the affected joint, suggests that RAR antagonists such as BMS-189453 may be useful as agents to treat rheumatoid arthritis and for determining the role of MMP in disease progression. "
2.	Rheumatoid Arthritis 02/01/2003 - "Improvement in clinical and histologic variables in 2 separate animal models, along with simultaneous reduction in MMP expression in the affected joint, suggests that RAR antagonists such as BMS-189453 may be useful as agents to treat rheumatoid arthritis and for determining the role of MMP in disease progression. "
3.	Congenital Abnormalities (Deformity) 05/01/2017 - "To establish a mouse model for the study of congenital defects, using exposure of pregnant females to the teratogen BMS-189453, a multiple retinoic acid competitive antagonist.We"
4.	Neural Tube Defects (Exencephaly) 05/01/2017 - "Newborns exposed in utero to BMS-189453 were affected by thymus aplasia or hypoplasia, and severe congenital anomalies of the central nervous system due to neural tube defects. "
5.	Inflammation (Inflammations) 02/01/2003 - "BMS-189453 treatment blocked the clinical progression of arthritis beyond soft tissue inflammation in the CIA model. "

Related Drugs and Biologics

1.	Matrix Metalloproteinases (MMPs)
2.	Tretinoin (Retinoic Acid)
3.	Teratogens
4.	Disulfiram (Antabuse)
5.	Alkaline Phosphatase
6.	Ethanol (Ethyl Alcohol)
7.	Alanine Transaminase (SGPT)