|1.||Raleigh, Daniel P: 2 articles (02/2011 - 08/2006)|
|2.||Meng, Fanling: 1 article (02/2011)|
|3.||Seidel, Ralf: 1 article (06/2009)|
|4.||Jha, Suman: 1 article (06/2009)|
|5.||Sellin, Daniel: 1 article (06/2009)|
|6.||Winter, Roland: 1 article (06/2009)|
|7.||Abedini, Andisheh: 1 article (08/2006)|
|8.||Cho, Jae-Hyun: 1 article (08/2006)|
|9.||Tracz, Sylvia M: 1 article (08/2006)|
|10.||Andersson, A: 1 article (06/2006)|
02/25/2011 - "Partially processed forms of proIAPP are found in amyloid deposits; most notable is a 48-residue intermediate, proIAPP(1-48), which includes the N-terminal pro-extension, but which has been properly processed at the C-terminus. "
08/01/2006 - "The N-terminal flanking region of proIAPP is detected in amyloid deposits; however, the C-terminal flanking region is not. "
04/01/2003 - "Other factors, such as impairment in the processing of proIAPP, the IAPP precursor, have been proposed to contribute to the development of islet amyloid deposits. "
06/01/2006 - "Also, proIAPP reactivity was more widespread in the intracellular amyloid-like aggregates in beta cells of transgenic mice than in human islet transplants, in which the intracellular amyloid-like deposits were larger, but the proIAPP labelling was restricted to small spots within the amyloid deposits. "
08/01/2006 - "Immunohistochemical studies implicate the presence of the heparan sulfate proteoglycan (HSPG) perlecan in islet amyloid deposits, suggesting a role for HSPGs in mediating amyloid deposition in type 2 diabetes and implicating a binding domain in the N-terminus of proIAPP. "
|2.||Type 2 Diabetes Mellitus (MODY)
06/26/2009 - "Human islet amyloid polypeptide (hIAPP), which is considered the primary culprit for beta-cell loss in type 2 diabetes mellitus patients, is synthesized in beta-cells of the pancreas from its precursor pro-islet amyloid polypeptide (proIAPP), which may be important in early intracellular amyloid formation as well. "
|1.||Amyloid (Amyloid Fibrils)
|2.||Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)
|4.||Islet Amyloid Polypeptide
|5.||pro-islet amyloid polypeptide