seryl-histidine

both amino acids function together as key catalytic amino acids in the active sites of diverse enzymes as the serine- and thiol-proteases, lipases, and esterases

Also Known As:

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Konovalova, G G: 2 articles (06/2014 - 01/2013)
2.	Lankin, V Z: 2 articles (06/2014 - 01/2013)
3.	Pisarenko, O I: 2 articles (06/2014 - 01/2013)
4.	Studneva, I M: 2 articles (06/2014 - 01/2013)
5.	Timoshin, A A: 2 articles (06/2014 - 01/2013)
6.	Tskitishvili, O V: 2 articles (06/2014 - 01/2013)
7.	Jia, L: 1 article (09/2019)
8.	Liu, L: 1 article (09/2019)
9.	Sun, S: 1 article (09/2019)
10.	Wei, Y F: 1 article (09/2019)

Related Diseases

1.	Myocardial Ischemia (Ischemic Heart Diseases) 01/01/2013 - "Effects of apelin-12 H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH (A12) and its modified analogue H-(NMe)Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Nle-Pro-Phe-OH (I) on activity of antioxidant enzymes, formation of malonic dialdehyde (MDA) and generation of reactive oxygen species (ROS) were studied in ex vivo and in vivo models of myocardial ischemia and reperfusion (I/R) injury in Wistar rats. " 06/01/2014 - "This study investigated the effects of peptide apelin-12 (H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, A12) and its novel structural analog (H-(N(α)Me)Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Nle-Pro-Phe-OH, AI) on myocardial antioxidant enzyme activities, lipid peroxidation, and reactive oxygen species formation in ex vivo and in vivo models of myocardial ischemia/reperfusion (I/R) injury. "
2.	Experimental Autoimmune Neuritis 09/01/2019 - "The objective of this paper was to study the effects of PYR-ARG-PRO-ARG-LEU-SER-HIS-YSGLY-PRO-MET-PRO-PHE-OH (APELIN-13) on the expression of inflammatory factors interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ) in rats with experimental autoimmune neuritis (EAN). "
3.	Neoplasms (Cancer) 04/01/2007 - "Direct antitumor activity of sea lamprey (Petromyzon marinus) gonadotropin-releasing hormone III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH(2); lGnRH-III) was described on several tumor cells. "
4.	Fibrosis (Cirrhosis) 03/01/2012 - "Fibrosis-induced rats received a CB2 receptor agonist (R,S)-3-(2-iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole (AM1241) (1 mg/kg b.wt.), an APJ antagonist [Ala(13)]-apelin-13 sequence: Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala (F13A) (75 μg/kg b.wt.), or vehicle daily during the last 5 weeks of the CCl(4) inhalation program. "

Related Drugs and Biologics

1.	arginylproline
2.	hydroxide ion
3.	lysylglycine
4.	Reactive Oxygen Species (Oxygen Radicals)
5.	Enzymes
6.	Antioxidants
7.	apelin-12 peptide
8.	Interleukin-6 (Interleukin 6)
9.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10.	Peptides (Polypeptides)