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Z- Asp- 2,6- dichlorobenzoyl- oxymethylketone

Also Known As:

Z-Asp-CMK

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Amino Acid Chloromethyl Ketones
    - Z-Asp-2,6-dichlorobenzoyl-oxymethylketone: 3

Experts

1.	Auberger, Patrick: 1 article (05/2005)
2.	Colosetti, Pascal: 1 article (05/2005)
3.	Cursio, Raffaele: 1 article (05/2005)
4.	Filippa, Nathalie: 1 article (05/2005)
5.	Gugenheim, Jean: 1 article (05/2005)
6.	Miele, Claudia: 1 article (05/2005)
7.	Van Obberghen, Emmanuel: 1 article (05/2005)
8.	Bucci, T J: 1 article (02/2001)
9.	Farhood, A: 1 article (02/2001)
10.	Gujral, J S: 1 article (02/2001)

Related Diseases

1.	Ischemia 05/01/2005 - "Z-Asp-cmk was injected intravenously, 2 min before induction of 120 min of normothermic liver ischemia. " 05/01/2005 - "The aim of this study was to evaluate the role of the pro-apoptotic molecule Fas Ligand (FasL) in 120 min normothermic ischemia-reperfusion (I-R) induced apoptosis in rat liver treated or not with Z-Asp-cmk caspase inhibitor. " 01/01/2000 - "Z-Asp-cmk (0.5 mg Z-Asp-cmk dissolved in 300 microl PBS solution containing 1% DMSO) was injected intravenously, 2 min prior to induction of 120 min ischemia. "
2.	Reperfusion Injury 02/01/2001 - "Moreover, the caspase inhibitor Z-Asp-cmk (2 mg/kg IV) had no significant effect on reperfusion injury. "
3.	Necrosis 01/01/2000 - "Serum activities of aminotransferases and the extent of liver congestion and necrosis were significantly (P < 0.001) decreased after treatment with Z-Asp-cmk. "

Related Drugs and Biologics

1.	Caspases
2.	Fas Ligand Protein (Fas Ligand)
3.	Solutions
4.	Dimethyl Sulfoxide (DMSO)
5.	Transaminases (Aminotransferases)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)