HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

multidrug resistance-associated protein 1

an organic anion transporter; may participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly; a number of isoforms are produced by alternative splicing
Also Known As:
ABCC1 protein, human; ABCC1 transport protein; ATP-binding cassette, sub-family C (CFTR/MRP), member 1, human; ATP-binding cassette, sub-family C (CFTR/MRP), member 1, mouse; ATP-binding cassette, subfamily C, member 1; Abcc1 protein, mouse; MPR1 transport protein; MRP1 protein, human; MRP1 protein, rat; Mrp1 protein, mouse
Networked: 128 relevant articles (4 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Postma, Dirkje S: 5 articles (12/2012 - 01/2005)
2. Scheper, Rik J: 5 articles (03/2009 - 11/2003)
3. Timens, Wim: 4 articles (12/2012 - 01/2005)
4. Mahjoubi, Frouzandeh: 3 articles (01/2013 - 05/2008)
5. Bates, Susan E: 3 articles (09/2011 - 02/2002)
6. Haber, Michelle: 3 articles (08/2009 - 10/2005)
7. Scheffer, George L: 3 articles (03/2009 - 11/2003)
8. van der Deen, Margaretha: 3 articles (01/2008 - 01/2005)
9. Baer, Maria R: 2 articles (04/2015 - 03/2005)
10. Chen, Siying: 2 articles (10/2014 - 06/2014)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. beta-Thalassemia (Cooley's Anemia)
3. Disease Progression
4. Carcinoma (Carcinomatosis)
05/01/2009 - "The aim of this study was to investigate the expression of multidrug resistance-associated protein 1 (MRP1) and to assess the possible associations with clinicopathological variables and patient outcome in primary ovarian carcinoma. "
05/01/2009 - "Expression of multidrug resistance-associated protein 1 in invasive ovarian carcinoma: implication for prognosis."
02/13/2004 - "In this study we show that P-glycoprotein in multidrug-resistant 2780AD human ovarian carcinoma cells and multidrug resistance-associated protein 1 in multidrug-resistant HT29col human colon carcinoma cells are predominantly located in Lubrol-based detergent-insoluble glycosphingolipid-enriched membrane domains. "
10/01/1999 - "Drug resistance-associated markers P-glycoprotein, multidrug resistance-associated protein 1, multidrug resistance-associated protein 2, and lung resistance protein as prognostic factors in ovarian carcinoma."
02/20/2002 - "The impact of the ABC transporters breast cancer resistance protein/mitoxantrone resistance associated transporter (BCRP/MXR), multidrug resistance-associated protein 1 (MRP1) and multidrug resistance gene-1/P-glycoprotein (MDR1/PGP) on the multidrug resistance (MDR) phenotype in chemoresistance and thermoresistance was investigated in the parental human gastric carcinoma cell line EPG85-257P, the atypical MDR subline EPG85-257RNOV, the classical MDR subline EPG85-257RDB and their thermoresistant counterparts EPG85-257P-TR, EPG85-257RNOV-TR and EPG85-257RDB-TR. "
5. Leukemia

Related Drugs and Biologics

1. P-Glycoprotein
2. Glutathione (Reduced Glutathione)
3. Janus Kinase 2
4. Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)
5. Smoke
6. major vault protein
7. Adenosine Triphosphate (ATP)
8. ATP-Binding Cassette Transporters (ABC Transporters)
9. Proteins (Proteins, Gene)
10. multidrug resistance-associated protein 2

Related Therapies and Procedures

1. Chinese Traditional Medicine (Traditional Chinese Medicine)
2. Drug Therapy (Chemotherapy)
3. Warm Ischemia
4. Combination Drug Therapy (Combination Chemotherapy)