2- (2- hydroxyethylsulfaryl)- 3- methyl- 1,4- naphthoquinone

induces phosphorylation of hepatocyte growth factor receptor, epidermal growth factor receptor, and other proteins; inhibits growth of pancreatic cancer cell lines

Also Known As:

2-(2-hydroxyethylsulfaryl)MNQ

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthoquinones: 418
        2-(2-hydroxyethylsulfaryl)-3-methyl-1,4-naphthoquinone: 1
- Quinones: 434
  - Naphthoquinones: 418
    - 2-(2-hydroxyethylsulfaryl)-3-methyl-1,4-naphthoquinone: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthoquinones: 418
      - 2-(2-hydroxyethylsulfaryl)-3-methyl-1,4-naphthoquinone: 1

Experts

1.	Carr, B I: 1 article (12/2000)
2.	Osada, S: 1 article (12/2000)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 12/01/2000 - "In the present study, we show that 2-(2-hydroxyethylsulfaryl)-3-methyl-1,4-naphthoquinone, or CPD 5, is a potent growth inhibitor for pancreas cancer cell lines (ID(50): 21.4 +/- 3.8, 31.8 +/- 2.7 and 55.2 +/- 4.5 microM for MiaPaCa, Panc-1 and BxPc3, respectively). "

Related Drugs and Biologics

1.	Growth Inhibitors