garenoxacin

09/01/2014 - "In conclusion, garenoxacin showed an efficacy rate of greater than 90% for suspected atypical pneumonia and confirmed atypical pneumonia. "
05/01/2007 - "Garenoxacin activity against isolates form patients hospitalized with community-acquired pneumonia and multidrug-resistant Streptococcus pneumoniae."
03/01/2003 - "These data suggest that garenoxacin should be effective in the treatment of community-acquired pneumonia and chronic obstructive pulmonary disease."
11/01/2019 - "The efficacy and safety of sitafloxacin and garenoxacin for the treatment of pneumonia in elderly patients: A randomized, multicenter, open-label trial."
01/01/2017 - "A Case of Macrolide-Refractory Mycoplasma pneumoniae Pneumonia in Pregnancy Treated with Garenoxacin."

06/01/2015 - "Previous studies have suggested that garenoxacin 400 mg once daily dose is appropriate for patients with normal to moderate renal disfunction against common bacteria of respiratory infections. "
10/01/2012 - "Efficacy and safety of garenoxacin in the treatment of upper respiratory tract infections."
06/01/2010 - "Pharmacokinetics of garenoxacin in elderly patients with respiratory tract infections."
05/01/2007 - "In this report, we studied 3087 CAP isolates from the SENTRY Antimicrobial Surveillance Program (1999-2005) worldwide and all respiratory tract infection (RTI) isolate population of pneumococci (14665 strains) grouped by antibiogram patterns against a new des-F(6)-quinolone, garenoxacin. "
05/01/2007 - "Garenoxacin, a novel des-F(6)-quinolone, was tested against 40423 pathogenic isolates associated with community-acquired respiratory tract infections (CA-RTIs). "

12/01/2003 - "In subsequent studies we used the neutropenic murine thigh infection model to determine if the magnitude of the AUC/MIC ratio needed for efficacy of garenoxacin varied among pathogens (including resistant strains). "
01/01/2003 - "Further study of garenoxacin is required, as it has great potential for use in the treatment of infections due to mycoplasmas and ureaplasmas."
06/01/2014 - "Garenoxacin in Skin and Skin Structure Infections Sustained due to Road Traffic Accident."
08/01/2012 - "On transmission electron microscopy observation, after exposure to garenoxacin at 24-30 h after infection, some C. "
08/01/2012 - "In a time-kill experiment, after exposure to garenoxacin at a concentration of 0.5 μg/ml at 0-6, 5-11, and 24-30 h after infection, the percentages of recoverable chlamydial inclusion-forming units were 11.1 ± 3.3, 0.6 ± 0.1, and 2.6 ± 0.5%, respectively. "

06/01/2015 - "Pharmacokinetic study of garenoxacin in severe renal failure patients."
06/01/2015 - "Consequently, for severe renal failure patients, the 400 mg once daily garenoxacin dose was expected to be effective against common bacteria of respiratory infections."
06/01/2015 - "Twenty severe renal failure patients with respiratory infection received single garenoxacin dose (200 mg and 400 mg). "
01/01/2017 - "Studies on the pharmacokinetics of the antibiotic garenoxacin (GRNX) in patients with renal insufficiency are lacking. "

08/01/2007 - "Of the 9 patients with acute bacterial sinusitis due to multidrug-resistant S pneumoniae, 8 achieved clinical cure with garenoxacin treatment. "
08/01/2007 - "Limited data are available regarding the effect of garenoxacin in the treatment of acute bacterial sinusitis. "
08/01/2007 - "In this population of patients with signs and symptoms of acute maxillary sinusitis, oral garenoxacin 400 mg QD for 5 or 10 days eradicated 94% of bacterial pathogens associated with acute bacterial sinusitis in this population and appeared to be well tolerated in adults."
12/01/2004 - "Data were obtained from three phase II clinical trials of garenoxacin administered orally as 400 mg once daily for 5 to 10 days for the treatment of community-acquired pneumonia, acute exacerbation of chronic bronchitis, and sinusitis. "
10/01/2012 - "Garenoxacin (400mg/day) was administered to patients with pharyngolaryngitis, tonsillitis, and otitis media for 5-7 days and to those with sinusitis for 7-10 days. "