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hydroxymatairesinol

a plant lignan from Norway spruce (Picea abies); structure in first source

Also Known As:

7'-hydroxymatairesinol; 7-hydroxymatairesinol; 7-hydroxymatairesinol potassium acetate

Networked: 12 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Lignans: 1113
        hydroxymatairesinol: 12

Experts

1.	Biasiotto, Giorgio: 2 articles (04/2020 - 10/2018)
2.	Di Lorenzo, Diego: 2 articles (04/2020 - 10/2018)
3.	Zanella, Isabella: 2 articles (04/2020 - 10/2018)
4.	Pacchetti, Barbara: 2 articles (01/2020 - 10/2018)
5.	Smeds, Annika: 2 articles (10/2018 - 05/2004)
6.	Saarinen, Niina M: 2 articles (01/2007 - 12/2004)
7.	Santti, Risto: 2 articles (01/2007 - 05/2004)
8.	Saarinen, Niina: 2 articles (03/2005 - 05/2004)
9.	Mäkelä, S I: 2 articles (02/2005 - 01/2001)
10.	Saarinen, N M: 2 articles (02/2005 - 01/2001)

Related Diseases

1.	Actinic Keratosis 07/01/2017 - "White spruce's known active principal compound, 7-hydroxymatairesinol, has anti-inflammatory activity, while phase II clinical trials have been completed on a birch bark emulsion for the treatment of actinic keratoses, epidermolysis bullosa, and the healing of split thickness graft donor sites. "
2.	Prostatic Neoplasms (Prostate Cancer) 03/01/2005 - "The purpose of this study was to investigate the effect of a plant lignan 7-hydroxymatairesinol (HMR) on LNCaP human prostate cancer xenografts in athymic mice. " 03/01/2005 - "Anticancer effects of a plant lignan 7-hydroxymatairesinol on a prostate cancer model in vivo."
3.	Hepatocellular Carcinoma (Hepatoma) 01/01/2007 - "In the present study, we examined the effect of 7-hydroxymatairesinol (HMR) and its mammalian metabolite, enterolactone (ENL), on AH109A hepatoma cell proliferation and invasion in vitro. " 01/01/2007 - "Hydroxymatairesinol and its mammalian metabolite enterolactone reduce the growth and metastasis of subcutaneous AH109A hepatomas in rats."
4.	Epidermolysis Bullosa 07/01/2017 - "White spruce's known active principal compound, 7-hydroxymatairesinol, has anti-inflammatory activity, while phase II clinical trials have been completed on a birch bark emulsion for the treatment of actinic keratoses, epidermolysis bullosa, and the healing of split thickness graft donor sites. "
5.	Neoplasms (Cancer) 05/01/2004 - "Hydroxymatairesinol (HMR), obtained from the heartwood of spruce (Picea abies), has been demonstrated to exert chemo-preventive effects on the development of mammary tumors in rats. " 12/20/2000 - "We studied the effects of a lignan, hydroxymatairesinol (HMR), and rye bran on intestinal tumor development in adenomatous polyposis colimultiple intestinal neoplasia (Apc)(Min) mice. " 10/31/2000 - "We studied the effects of a lignan, hydroxymatairesinol (HMR), and rye bran on intestinal tumor development in adenomatous polyposis colimultiple intestinal neoplasia (Apc)(Min) mice. "

Related Drugs and Biologics

1.	Lignans
2.	Emulsions
3.	2,3-bis(3'-hydroxybenzyl)butyrolactone (enterolactone)
4.	anthracene
5.	Neuroprotective Agents
6.	Iron
7.	Sugars
8.	matairesinol
9.	secoisolariciresinol
10.	lariciresinol

Related Therapies and Procedures

1.	Oral Administration