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fibrinogen Caracas V

cysteine replaces serine at position 532 of the Aalpha subunit

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Blood Coagulation Factors: 5376
      - Fibrinogen: 15409
        Abnormal Fibrinogens: 8
        fibrinogen Caracas V: 2
    - Acute-Phase Proteins: 5159
      - Fibrinogen: 15409
        Abnormal Fibrinogens: 8
        fibrinogen Caracas V: 2
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Fibrinogen: 15409
    - Abnormal Fibrinogens: 8
      - fibrinogen Caracas V: 2

Experts

1.	Marchi, R: 2 articles (08/2000 - 07/2000)
2.	de Bosch, N B: 2 articles (08/2000 - 07/2000)
3.	Arocha Piñango, C L: 1 article (08/2000)
4.	Grimbergen, J: 1 article (08/2000)
5.	Haverkate, F: 1 article (08/2000)
6.	Koopman, J: 1 article (08/2000)
7.	Lundberg, U: 1 article (08/2000)
8.	Torres, A: 1 article (08/2000)
9.	Arocha-Piñango, C L: 1 article (07/2000)
10.	Collet, J P: 1 article (07/2000)

Related Diseases

1.	Thrombosis (Thrombus) 08/01/2000 - "Fibrinogen Caracas V, an abnormal fibrinogen with an Aalpha 532 Ser-->Cys substitution associated with thrombosis." 07/15/2000 - "Therefore, this fibrinogen shows a striking similarity to the fibrinogen Dusart, allowing us to confirm that the alphaC-terminal part of fibrinogen plays an important role in fibrin structure, and to conclude that the anomaly of fibrin network observed in fibrinogen Caracas V is responsible for a deficient thrombus lysis."
2.	Thrombophilia 07/15/2000 - "In the present work, fibrinogen Caracas V is further characterized in order to understand the relationship between the structural defect and thrombophilia. "

Related Drugs and Biologics

1.	Fibrinogen (Factor I)
2.	Fibrin
3.	fibrinogen Dusard