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ORI 1202

a polyamine transporter inhibitor that inhibits cell growth in conjunction with alpha-difluoromethylornithine; structure in first source

Also Known As:

ORI-1202

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Burns, M R: 1 article (11/2000)
2.	Cai, F: 1 article (11/2000)
3.	Carlson, C L: 1 article (11/2000)
4.	Devens, B H: 1 article (11/2000)
5.	O'Day, C L: 1 article (11/2000)
6.	Vanderwerf, S M: 1 article (11/2000)
7.	Webb, H K: 1 article (11/2000)
8.	Weeks, R S: 1 article (11/2000)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 11/25/2000 - "Human breast, prostate, and bladder carcinoma cell lines and melanoma cell lines show ORI 1202 EC(50) values in the low micromolar range when tested in conjunction with DFMO. "
2.	Carcinoma (Carcinomatosis) 11/25/2000 - "Human breast, prostate, and bladder carcinoma cell lines and melanoma cell lines show ORI 1202 EC(50) values in the low micromolar range when tested in conjunction with DFMO. "
3.	Breast Neoplasms (Breast Cancer) 11/25/2000 - "When ORI 1202 (45 mg/kg, i.p., tidx5) and DFMO (1% in drinking water) were delivered over 14 days, MDA-MB-231 breast tumor xenografts in nude mice showed 50% growth inhibition. "

Related Drugs and Biologics

1.	Drinking Water