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B 5354c

a sphingosine kinase inhibitor; structure in first source

Also Known As:

B-5354c

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        Aminobenzoates: 1
        para-Aminobenzoates: 43
        B 5354c: 2
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - Aminobenzoates: 1
        para-Aminobenzoates: 43
        B 5354c: 2

Experts

1.	Cuvillier, Olivier: 1 article (07/2008)
2.	Doumerc, Nicolas: 1 article (07/2008)
3.	Golzio, Muriel: 1 article (07/2008)
4.	Kohama, Takafumi: 1 article (07/2008)
5.	Malavaud, Bernard: 1 article (07/2008)
6.	Naymark, Maria: 1 article (07/2008)
7.	Pchejetski, Dimitri: 1 article (07/2008)
8.	Teissié, Justin: 1 article (07/2008)
9.	Waxman, Jonathan: 1 article (07/2008)
10.	Ikari, Syusuke: 1 article (03/2004)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2008 - "In vivo, camptothecin and B-5354c alone display a limited effect on tumor growth in PC-3 cells, whereas in combination there is a synergy of effect on tumor size with a significant increase in the ceramide to S1P sphingolipid ratio. "
2.	Hemolysis 03/26/2004 - "Furthermore, dl-threo-dihydrosphingosine and B-5354c, isolated from a novel marine bacterium, both sphingosine kinase inhibitors, blocked the toxin-induced hemolysis and production of S1P and caused sphingosine to accumulate. "

Related Drugs and Biologics

1.	Sphingosine
2.	Sphingolipids
3.	Ceramides
4.	Camptothecin
5.	sphingosine kinase
6.	safingol (sphinganine)