|1.||Ito, Yuki: 2 articles (01/2013 - 05/2007)|
|2.||Nakayama, Jun: 2 articles (01/2013 - 05/2007)|
|3.||Kobayashi, Tatsuya: 2 articles (01/2013 - 05/2007)|
|4.||Sugahara, Kazuyuki: 2 articles (01/2013 - 10/2007)|
|5.||Habuchi, Osami: 2 articles (02/2010 - 05/2007)|
|6.||Mizumoto, Shuji: 1 article (01/2013)|
|7.||Hongo, Kazuhiro: 1 article (01/2013)|
|8.||Yan, Huimin: 1 article (01/2013)|
|9.||Yamada, Shuhei: 1 article (01/2013)|
|10.||Watanabe, Moto: 1 article (01/2013)|
|1.||Colorectal Neoplasms (Colorectal Cancer)
05/12/2007 - "ISH using an RNA probe specific for GalNAc4S-6ST revealed that it was expressed in colorectal cancer cells. "
05/12/2007 - "In the present study, we analyzed expression of GalNAc4S-6ST mRNA in colorectal cancer by combining real-time RT-PCR with in situ hybridization (ISH) using archived formalin-fixed and paraffin-embedded tissue sections. "
05/12/2007 - "The utility of formalin-fixed and paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells."
05/12/2007 - "Taken together, we show that real-time RT-PCR combined with ISH is useful to investigate quantitatively GalNAc4S-6ST mRNA expression in formalin-fixed and paraffin-embedded tissue sections, and that GalNAc4S-6ST expressed by colorectal cancer cells plays a minor role in tumor progression."
01/01/2013 - "Here, we reveal that GalNAc4S-6ST transcripts were detected in astrocytic tumors derived from all 30 patients examined using quantitative reverse transcription-PCR analysis. "
01/01/2013 - "Although involvements of CS-E in neuronal cell functions have been extensively analyzed, the role of GalNAc4S-6ST in astrocytic tumor progression remains unknown. "
01/01/2013 - "Role of GalNAc4S-6ST in astrocytic tumor progression."
05/12/2007 - "However, the role of GalNAc4S-6ST in tumor progression remains unknown. "
01/01/2013 - "Thus, our findings indicate that GalNAc4S-6ST mRNA expressed by astrocytic tumor cells is associated with poor patient prognosis likely by enhancing CS-E-mediated tumor cell motility in the presence of PTN and/or MK."
|3.||Neoplasm Metastasis (Metastasis)
01/01/2013 - "These results provide clear evidence that CS chain-containing E-units and/or GalNAc4S-6ST play a crucial role in pulmonary metastasis at least through the increased adhesion and the invasive capacity of LLC cells and also provides insights into future drug targets for anticancer treatment."
01/01/2013 - "Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis."
|4.||Glioblastoma (Glioblastoma Multiforme)
01/01/2013 - "We then tested whether CS-E enhanced haptotaxic migration of glioblastoma U251-MG cells that endogenously express both the CS-E's scaffold tyrosine phosphatase ζ (PTPζ) and GalNAc4S-6ST, in the presence of CS-E's preferred ligands, pleiotrophin (PTN) or midkine (MK), using a modified Boyden chamber method. "
|1.||Messenger RNA (mRNA)
|5.||RNA (Ribonucleic Acid)
|7.||Chondroitin Sulfates (Chondroitin Sulfate)