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HO 2434

structure in first source

Also Known As:

HO-2434; MEX-NH

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Propylamines: 1
    - Mexiletine: 762
      - HO 2434: 1
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Phenyl Ethers: 8
        Mexiletine: 762
        HO 2434: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - HO 2434: 1

Experts

1.	Hideg, K: 1 article (11/2000)
2.	Kalai, T: 1 article (11/2000)
3.	Kuppusamy, P: 1 article (11/2000)
4.	Li, H: 1 article (11/2000)
5.	Xu, K Y: 1 article (11/2000)
6.	Zhou, L: 1 article (11/2000)
7.	Zweier, J L: 1 article (11/2000)

Related Diseases

1.

11/01/2000 - "The present study establishes that the compound MEX-NH provides marked protection against ischemia/reperfusion-induced contractile dysfunction in isolated hearts. "
11/01/2000 - "Hearts were either untreated or treated with 25 microM MEX-NH or MEX for 1 min before ischemia. "
11/01/2000 - "The efficacy and mechanism of protection of a new 2,2,5, 5-tetramethylpyrroline derivative of mexiletine, MEX-NH, against ischemia/reperfusion-induced cardiac dysfunction are reported. "

Related Drugs and Biologics

1.	Mexiletine (Mexitil)