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OSU8 1

Also Known As:

(4-(N-hydroxyamino)-2-isobutyl-3-methylsuccinyl)-3-(5,6,7,8-tetrahydro-1-naphthyl)alanine-N-methylamide; OSU8-1

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Alanine: 4133
    - OSU8 1: 1
Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Hydroxamic Acids: 239
      - OSU8 1: 1
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxamic Acids: 239
      - OSU8 1: 1

Experts

1.	Endo, T: 1 article (10/2000)
2.	Hanakawa, Y: 1 article (10/2000)
3.	Hashimoto, K: 1 article (10/2000)
4.	Higashiyama, S: 1 article (10/2000)
5.	Matsuzawa, Y: 1 article (10/2000)
6.	Miyagawa, J I: 1 article (10/2000)
7.	Nakagawa, T: 1 article (10/2000)
8.	Ohmoto, H: 1 article (10/2000)
9.	Shirakata, Y: 1 article (10/2000)
10.	Taniguchi, N: 1 article (10/2000)

Related Diseases

1.

Wounds and Injuries (Trauma)

10/16/2000 - "The application of OSU8-1 to wound sites in mice greatly retarded reepithelialization as the result of a failure in keratinocyte migration, but this effect could be overcome if recombinant soluble HB-EGF was added along with OSU8-1. "
10/16/2000 - "OSU8-1, an inhibitor of EGFR ligand shedding, abrogated the wound-induced activation of EGFR and caused suppression of keratinocyte migration in vitro. "

Related Drugs and Biologics

1.	Heparin-binding EGF-like Growth Factor (HB-EGF)
2.	Ligands