|1.||Ouyang, Wenjun: 20 articles (02/2015 - 02/2007)|
|2.||Sabat, Robert: 17 articles (01/2015 - 08/2004)|
|3.||Gao, Bin: 16 articles (09/2015 - 02/2004)|
|4.||Wolk, Kerstin: 15 articles (01/2015 - 08/2004)|
|5.||Renauld, Jean-Christophe: 15 articles (11/2014 - 08/2002)|
|6.||Fouser, Lynette A: 12 articles (12/2015 - 05/2004)|
|7.||Dumoutier, Laure: 10 articles (06/2013 - 08/2002)|
|8.||Kolls, Jay K: 9 articles (03/2015 - 03/2008)|
|9.||Mühl, Heiko: 9 articles (01/2015 - 06/2007)|
|10.||Pfeilschifter, Josef: 9 articles (01/2015 - 06/2007)|
07/21/2011 - "Blocking of LTβR signaling dramatically reduced intestinal IL-22 production after C. rodentium infection. "
03/16/2012 - "Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection: potential role in protection against lung epithelial damages."
10/16/2014 - "Here, we report a critical role for interleukin-22 (IL-22) in systemic protection against bacterial pathobionts that translocate into the circulation after infection with the pathogen Clostridium difficile. "
01/01/2013 - "IL-22 is mainly produced by IFNγ-secreting cells but is dispensable for host protection against Mycobacterium tuberculosis infection."
01/01/2011 - "Collectively, these data indicate that IL-22 produced during LM infection must play a role other than clearance of LM or protection of tissues from pathogen- or immune-mediated damage."
|2.||Bacterial Infections (Bacterial Infection)
09/01/2015 - "In addition, IL-22 treatment also ameliorates bacterial infection and kidney injury, two major complications associated with severe AH. "
02/01/2012 - "Here we found that Ahr(-/-) mice had a considerable deficit in ILC22 cells that resulted in less secretion of IL-22 and inadequate protection against intestinal bacterial infection. "
12/14/2012 - "Interleukin-22 (IL-22) is central to host protection against bacterial infections at barrier sites. "
01/01/2013 - "In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti-helminth immunity. "
02/01/2015 - "Our results suggest mullet IL-22 plays an important role in the immune defense against bacterial infection and has the potential to be used to treat bacterial diseases in fish. "
11/01/2015 - "This study will help identify new therapeutic strategies for OA, especially the targeting of IL-22 to decrease inflammation."
07/01/2013 - "In this study, we show that IL-22 deficiency in donor T cells can decrease the severity of aGVHD, while limiting systemic and local inflammation in aGVHD target organs. "
04/01/2013 - "This study was undertaken to investigate the mechanism of action and role of systemic IL-22 in modulating target organ inflammation. "
11/15/2011 - "This study examined whether IL-22 could suppress allergic airway inflammation and its mechanism of action. "
05/01/2011 - "Consistent with that, studies of mouse model systems have identified a critical role for signaling by IL-22 through its receptor (IL-22R) in the promotion of antimicrobial immunity, inflammation and tissue repair at barrier surfaces. "
01/01/2011 - "The purpose of this study is to assess the inhibitory effects of IL-22 on human RCC cell line A498 and to investigate the possible mechanisms underlying the anti-tumor effects of this cytokine. "
10/01/2015 - "The cytokine interleukin-22 (IL-22), which is produced by T cells and natural killer cells, is associated with tumorigenesis and tumor progression in cancers. "
04/14/2015 - "IL-22 promoted tumor growth in BALB/c nude mice; however, this effect was reversed by adding a STAT3 inhibitor. "
10/01/2014 - "The cytokine IL-22, which is produced by T cells and NK cells, is associated with tumorigenesis and tumor progression in cancers. "
06/01/2014 - "This review summarizes current findings on functions of IL-22 in association with general mechanisms for tumorigenesis as well as specific contributions to particular cancers, and ponders how best to approach further research in the field. "
01/01/2014 - "Neutralization of IL-22 after onset of arthritis resulted in significant increase in Th1 responses and significantly reduced severity of arthritis. "
01/01/2014 - "IL-22 deficient mice have reduced incidence of arthritis. "
03/01/2015 - "Recent findings suggest that not only the expression of IL-22 is abnormal both in RA patients and in arthritis mice but also the aberrant IL-22 performs significantly in disease onset of RA. "
06/01/2014 - "The Th17-associated cytokine IL-22 also appears to have a pathogenic role in autoimmune arthritis, particularly in promoting proinflammatory responses by synovial fibroblasts and osteoclastogenesis. "
01/01/2014 - "We show for the first time that IL-22 plays a dual role: protective prior to the onset of arthritis and pathogenic after onset of arthritis. "
|1.||Interleukin-17 (Interleukin 27)
|2.||Interleukin-23 (Interleukin 23)
|3.||Interleukin-6 (Interleukin 6)
|4.||STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)
|5.||Interleukin-10 (Interleukin 10)
|6.||Messenger RNA (mRNA)
|1.||Drug Therapy (Chemotherapy)
|4.||Bone Marrow Transplantation (Transplantation, Bone Marrow)